Calicophoron daubneyi is the primary rumen fluke (RF) found in Europe in ruminants and infection is more common in cattle than in sheep. The incidence of RF has appeared to increase greatly throughout Europe in the last 10–15 years, with outbreaks of clinical paramphistomosis confirmed in ruminants in many countries, including Great Britain and Ireland. Clinical disease, due to immature stages developing in the small intestine, appears infrequently but can occur, usually in the autumn or winter within weeks of beginning to graze wet pasture. Although disease due to adult RF has not been proven, subclinical production losses have been attributed to adult RF infection by some researchers. As the intermediate host for RF and the liver fluke (Fasciola hepatica) is the mud snail (Galba truncatula), similar habitats and environmental conditions favour both parasites. There may, however, be differences in parasite development and interactions within both the final and intermediate hosts. No anthelminthic product is licensed for treatment of ruminants for RF in the UK. However, oxyclozanide, licensed for the treatment of adult F. hepatica infection, has been shown to have activity, but it may be more effective against the adult than the immature stages. The future prevalence of RF due to climate change and limited treatment options is unpredictable. Infection and clinical disease could become more common and RF is worthy of further research.

Calicophoron daubneyi是欧洲反刍动物的主要瘤胃吸虫（RF），感染牛比羊更常见。在过去的 10 到 15 年中，整个欧洲的 RF 发病率似乎大大增加，包括英国和爱尔兰在内的许多国家的反刍动物中都证实了临床寄生虫病的爆发。由于小肠发育的不成熟阶段，临床疾病很少出现，但可能发生，通常在秋季或冬季开始放牧湿牧场后的几周内。尽管成人 RF 引起的疾病尚未得到证实，但一些研究人员已将亚临床生产损失归因于成人 RF 感染。作为RF中间宿主和肝吸虫（肝片吸虫）是泥蜗牛（Galba truncatula），类似的栖息地和环境条件有利于这两种寄生虫。然而，最终宿主和中间宿主内的寄生虫发育和相互作用可能存在差异。在英国，没有任何驱虫产品被许可用于治疗反刍动物的 RF。然而，已获准用于治疗成人肝镰刀菌感染的氧氯氮杂已被证明具有活性，但它可能比未成熟阶段对成人更有效。由于气候变化和有限的治疗选择，未来 RF 的流行是不可预测的。感染和临床疾病可能会变得更加普遍，RF 值得进一步研究。