Omalizumab is a safe and effective treatment for antihistamine-refractory chronic spontaneous urticaria (CSU) but is insufficient in one-third of patients. For serious cases in which omalizumab is ineffective, cyclosporine or methotrexate may be preferred. Most drug trials in CSU have focused on omalizumab or cyclosporine monotherapy.

中文翻译：

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药物治疗抗组胺难治性慢性自发性荨麻疹的疗效：现实生活数据。


奥马珠单抗是一种安全有效的治疗抗组胺药难治性慢性自发性荨麻疹 (CSU) 的方法，但对于三分之一的患者来说效果不佳。对于奥马珠单抗无效的严重病例，可能首选环孢素或甲氨蝶呤。科罗拉多州立大学的大多数药物试验都集中在奥马珠单抗或环孢素单一疗法。