Psoriasis is a chronic inflammatory skin disease, which the mechanisms behind its initiation and development are related to many factors. DMSCs (dermal mesenchymal stem cells) represent an important member of the skin microenvironment and play an important role in the surrounding environment and in neighbouring cells, but they are also affected by the microenvironment. We studied the glucose metabolism of DMSCs in psoriasis patients and a control group to reveal the relationship among glucose metabolism, cell proliferation activity，and VEC (vascular endothelial cell) differentiation in vitro, we demonstrated the biological activity and molecular mechanisms of DMSCs in psoriasis.

中文翻译：

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牛皮癣中葡萄糖代谢干扰的真皮间充质干细胞增殖和分化失调。

银屑病是一种慢性炎症性皮肤病，其发生和发展的机制与多种因素有关。DMSCs（真皮间充质干细胞）代表皮肤微环境的重要成员，在周围环境和邻近细胞中发挥重要作用，但它们也受到微环境的影响。我们在银屑病患者和对照组中研究了DMSCs的糖代谢，以揭示糖代谢、细胞增殖活性和体外VEC（血管内皮细胞）分化之间的关系，我们证明了DMSCs在银屑病中的生物学活性和分子机制。