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Enriched Au nanoclusters with mesoporous silica nanoparticles for improved fluorescence/computed tomography dual‐modal imaging
Cell Proliferation ( IF 5.9 ) Pub Date : 2021-02-25 , DOI: 10.1111/cpr.13008 Yifang Yuan 1 , Ronghui Zhou 2 , Ting Li 2 , Shuang Qu 1 , Hua Bai 1 , Jiawu Liang 1 , Xiaoxiao Cai 2 , Bin Guo 1
Cell Proliferation ( IF 5.9 ) Pub Date : 2021-02-25 , DOI: 10.1111/cpr.13008 Yifang Yuan 1 , Ronghui Zhou 2 , Ting Li 2 , Shuang Qu 1 , Hua Bai 1 , Jiawu Liang 1 , Xiaoxiao Cai 2 , Bin Guo 1
Affiliation
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Au nanoclusters (AuNCs) have been used widely in fluorescence bio‐imaging because of their good fluorescence, small particle size and non‐cytotoxicity. AuNCs are also efficient in computed tomography (CT) imaging. Hence, a dual‐modal imaging probe can be constructed without any complicated modification processes by exploiting the excellent performance of AuNCs. In the present study, AuNCs were enriched with mesoporous silica nanoparticles (MSNs) to obtain enhanced fluorescence/CT dual‐modal imaging, which was capable of acquiring more imaging information for diseases compared with single‐mode imaging.
中文翻译：
带有中孔二氧化硅纳米粒子的富金纳米团簇，用于改善荧光/计算机断层扫描双峰成像
金纳米团簇（AuNCs）由于其良好的荧光，小粒径和无细胞毒性而被广泛用于荧光生物成像。AuNC在计算机断层扫描（CT）成像中也很有效。因此，通过利用AuNC的出色性能，可以构建双模态成像探针，而无需进行任何复杂的修饰过程。在本研究中，AuNCs富含中孔二氧化硅纳米颗粒（MSN），以获得增强的荧光/ CT双模态成像，与单模成像相比，它能够获取更多的疾病成像信息。
更新日期：2021-04-02
中文翻译：
带有中孔二氧化硅纳米粒子的富金纳米团簇，用于改善荧光/计算机断层扫描双峰成像
金纳米团簇（AuNCs）由于其良好的荧光，小粒径和无细胞毒性而被广泛用于荧光生物成像。AuNC在计算机断层扫描（CT）成像中也很有效。因此，通过利用AuNC的出色性能，可以构建双模态成像探针，而无需进行任何复杂的修饰过程。在本研究中，AuNCs富含中孔二氧化硅纳米颗粒（MSN），以获得增强的荧光/ CT双模态成像，与单模成像相比，它能够获取更多的疾病成像信息。
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