Viable biorefinery requires a robust and cost-competitive method of biomass fractionation. Here, we design green and efficient flow-through reactor for biomass fractionation. Aqueous formic acid was used as a solvent at mild temperatures. The time course study verified a rapid flow-through fractionation of wheat straw in 20 min at 130 °C involving synergetic actions of acid hydrolysis of hemicellulose and lignin dissolution. The obtained fractionation attained 76.3 % of lignin yield and 69.8 % of sugars yield without measurable degradation of hemicelluloses. More importantly, lignin fractionation showed well-preserved inter-unit linkages as indicated by the 76.4 % retention of aryl ether bond. The exponential model was established and well described the relationships between fractionation conditions and kinetics of lignin solubilization. This rapid flow-through reactor/fractionation promises to be a very practical equipment/strategy for biomass fractionation with competitive products.

可行的生物精炼厂需要一种可靠且具有成本竞争力的生物质分馏方法。在这里，我们设计了用于生物质分馏的绿色高效流通式反应器。在温和的温度下，甲酸水溶液用作溶剂。时程研究证明了在130°C下20分钟内小麦秸秆的快速流分馏涉及半纤维素的酸水解和木质素溶解的协同作用。所获得的分级分离获得了木质素收率的76.3％和糖收率的69.8％，而半纤维素的降解没有可测量的。更重要的是，木质素分级分离显示保存完好的单元间键，如芳基醚键保留76.4％所示。建立了指数模型，并很好地描述了分离条件与木质素溶解动力学之间的关系。