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TSP50 promotes hepatocyte proliferation and tumour formation by activating glucose‐6‐phosphate dehydrogenase (G6PD)
Cell Proliferation ( IF 5.9 ) Pub Date : 2021-02-25 , DOI: 10.1111/cpr.13015 Xiaojun Zhang 1, 2 , Feng Gao 1, 2 , Huihan Ai 1 , Shuyue Wang 1 , Zhenbo Song 2 , Lihua Zheng 2 , Guannan Wang 2 , Ying Sun 2 , Yongli Bao 1
Cell Proliferation ( IF 5.9 ) Pub Date : 2021-02-25 , DOI: 10.1111/cpr.13015 Xiaojun Zhang 1, 2 , Feng Gao 1, 2 , Huihan Ai 1 , Shuyue Wang 1 , Zhenbo Song 2 , Lihua Zheng 2 , Guannan Wang 2 , Ying Sun 2 , Yongli Bao 1
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Hepatocellular carcinoma (HCC) is a common malignant tumour with high morbidity and mortality. Metabolic regulation by oncogenes is necessary for tumour growth. Testes‐specific protease 50 (TSP50) has been found to promote cell proliferation in multiple tumour types. However, the mechanism that TSP50 promotes HCC progression are not known.
中文翻译：
TSP50通过激活6-6磷酸葡萄糖脱氢酶（G6PD）促进肝细胞增殖和肿瘤形成
肝细胞癌（HCC）是一种常见的恶性肿瘤，具有较高的发病率和死亡率。癌基因的代谢调节对于肿瘤的生长是必需的。已发现睾丸特异性蛋白酶50（TSP50）可以促进多种肿瘤类型的细胞增殖。但是，TSP50促进HCC进展的机制尚不清楚。
更新日期：2021-04-02
中文翻译：
TSP50通过激活6-6磷酸葡萄糖脱氢酶（G6PD）促进肝细胞增殖和肿瘤形成
肝细胞癌（HCC）是一种常见的恶性肿瘤，具有较高的发病率和死亡率。癌基因的代谢调节对于肿瘤的生长是必需的。已发现睾丸特异性蛋白酶50（TSP50）可以促进多种肿瘤类型的细胞增殖。但是，TSP50促进HCC进展的机制尚不清楚。
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