This experimental study investigates the radioactivation of titanium during proton therapy. Titanium is a commonly used material for implants. Because of its fixed position, the activation of those implants might be useful for post-irradiation field. Various titanium samples are irradiated at the West German Proton Therapy Centre Essen. The activities of the produced radionuclides are obtained with a low-level gamma-ray spectrometry system at the Dortmund Low Background Facility. Furthermore, an irradiated titanium sample is placed in a pre-clinic PET/CT scanner to investigate the potential of the implants for range verification. With the gamma-ray spectrometry technique a number of radionuclides are identified as candidates for range verification with delayed secondary gamma-rays. Furthermore, activation cross sections are calculated with the activities for the identified radionuclides. The depth distribution of the activity as obtained with the PET/CT scans has a characteristic rise towards the distal end similar to the depth dose curve.

这项实验研究调查了质子治疗过程中钛的放射性。钛是植入物的常用材料。由于其固定位置，这些植入物的激活可能对辐照后领域很有用。西德质子治疗中心埃森辐射了各种钛样品。产生的放射性核素的活性是在多特蒙德低背景实验室的低能级伽马射线能谱系统获得的。此外，将辐照过的钛样品放置在临床前PET / CT扫描仪中，以研究植入物用于范围验证的潜力。使用伽马射线光谱技术，可以将许多放射性核素确定为使用延迟的二次伽马射线进行范围验证的候选者。此外，用确定的放射性核素的活度计算活化截面。通过PET / CT扫描获得的活动深度分布与深度剂量曲线相似，具有朝向远端的特征上升。