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COVID-19 infection and cardiac angiosarcoma: a dangerous combination—a case report
The Cardiothoracic Surgeon ( IF 0.5 ) Pub Date : 2021-02-24 , DOI: 10.1186/s43057-021-00042-7
Santiago A Endara 1 , Gerardo A Dávalos 1 , Gabriel A Molina 2 , Aldo B Zavala 3 , Patricia M Ponton 4 , Maribel Brito 4 , Carlos Nieto 5 , Vladimir E Ullauri 5
Affiliation  

The COVID-19 pandemic has strained all medical systems, especially in countries like Ecuador, where health services were already limited. These conditions, combined with a deadly and unusual disease, like primary heart angiosarcoma, can lead to severe outcomes. Angiosarcomas represent the most common and aggressive primary malignant heart tumor; regretfully, its clinical manifestations are vague and can be easily missed. Most patients become symptomatic when there is local invasion, embolization, or metastases, leading to late diagnosis and poor survival. High clinical awareness, adequate diagnosis, and prompt treatment are vital in these rare diseases, in which time is of paramount importance. We report the case of a 28-year-old female who had cough, hemoptysis, and ground-glass opacities in the CT (computed tomography). Since Ecuador is in the middle of this pandemic, she was misdiagnosed and mistreated. Primary heart angiosarcoma was diagnosed, and regretfully, the patient suffered multiple complications due to diagnosis and died. To this day, most cardiac angiosarcomas are found in a late-stage with distal metastasis and advanced local invasion. Sadly, this tumor is frequently missed due to its incidence and broad-spectrum of clinical symptoms. Considering that its manifestations can be misleading, misdiagnosis can occur, especially in pandemic times. Therefore, knowledge of other pathologies prevents COVID-19 from overshadowing other diagnoses, hence preventing delayed diagnosis or even misdiagnosis and consequent adverse outcomes for patients.

中文翻译:


COVID-19 感染和心脏血管肉瘤:危险的组合——病例报告



COVID-19 大流行给所有医疗系统带来了压力,特别是在厄瓜多尔这样的国家,那里的卫生服务本来就很有限。这些情况与致命且不寻常的疾病(如原发性心脏血管肉瘤)相结合,可能会导致严重的后果。血管肉瘤是最常见和最具侵袭性的原发性恶性心脏肿瘤;遗憾的是,其临床表现并不明确,很容易被忽视。大多数患者在局部浸润、栓塞或转移时出现症状,导致诊断较晚和生存率低。高度的临床认识、充分的诊断和及时的治疗对于这些罕见疾病至关重要,其中时间至关重要。我们报告一例 28 岁女性的病例,她出现咳嗽、咯血,CT(计算机断层扫描)显示毛玻璃样阴影。由于厄瓜多尔正处于这场大流行之中,她被误诊和虐待。诊断为原发性心脏血管肉瘤,遗憾的是,患者因诊断出现多种并发症而死亡。迄今为止,大多数心脏血管肉瘤已处于晚期,伴有远端转移和晚期局部浸润。遗憾的是,由于这种肿瘤的发病率和临床症状广泛,经常被漏诊。考虑到其表现可能会产生误导,因此可能会发生误诊,尤其是在大流行时期。因此,了解其他病理学可以防止 COVID-19 掩盖其他诊断,从而防止延误诊断甚至误诊以及由此给患者带来的不良后果。
更新日期:2021-02-24
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