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Protection strategy against outbreak of COVID-19 at a tertiary hematology-oncology: strengths and pitfalls
Infectious Agents and Cancer ( IF 3.1 ) Pub Date : 2021-02-24 , DOI: 10.1186/s13027-021-00356-5
Dominic Kaddu-Mulindwa 1 , Lorenz Thurner 1 , Moritz Bewarder 1 , Niels Murawski 1 , Manfred Ahlgrimm 1 , Thorsten Pfuhl 2 , Barbara Gärtner 3 , Sigrun Smola 2 , Stephan Stilgenbauer 1
Affiliation  

Due to the worldwide COVID-19 outbreak it is mandatory for health care workers to develop containment strategies. Recently published data showed, that cancer patients might have a higher risk for severe course of the disease. We therefore developed a strategy of screening and containment for SARS-CoV-2 for hospitalized cancer patients. Our approach includes a temporary isolation in a so-called floating zone and testing strategy for screening of asymptomatic individuals by pooling of samples before RT-PCR amplification. Patients as far as health care professionals got tested twice a week. Nurses and physicians entered the floating zone with full body protection. Within 8 weeks we tested 418 individuals (professionals and patients) in total. Only 2 patients had COVID-19 without documented further transmission of SARS-CoV-2. We therefore think that our strategy might be a useful approach to protect inpatients with cancer at high risk for SARS-CoV-2 infection during this ongoing pandemic.

中文翻译:


三级血液肿瘤科预防 COVID-19 爆发的保护策略:优势和缺陷



由于全球范围内 COVID-19 的爆发,医护人员必须制定遏制策略。最近公布的数据显示,癌症患者出现严重病程的风险可能更高。因此,我们制定了针对住院癌症患者的 SARS-CoV-2 筛查和遏制策略。我们的方法包括在所谓的浮动区中进行临时隔离,以及通过在 RT-PCR 扩增之前汇集样本来筛查无症状个体的测试策略。就医疗保健专业人员而言,患者每周接受两次检查。护士和医生在全身防护的情况下进入漂浮区。 8 周内,我们总共测试了 418 人(专业人士和患者)。只有 2 名患者患有 COVID-19,但没有记录到 SARS-CoV-2 进一步传播。因此,我们认为我们的策略可能是一种有用的方法,可以在这场持续的大流行期间保护 SARS-CoV-2 感染高风险的住院癌症患者。
更新日期:2021-02-24
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