Infertility affects 48.5 million couples worldwide with a prevalence estimated at 3.5–16.7% in low- and middle-income countries (LMIC), and as high as 30–40% in Sub-Saharan Africa. ART services are not accessible to the majority of these infertile couples due to the high cost of treatments in addition to cultural, religious and legal barriers. Infertility and childlessness, particularly in LMIC, have devastating consequences, which has resulted in considerable interest in developing affordable IVF procedures. However, there is a paucity of evidence on the safety, efficiency and ability to replicate techniques under different field conditions, and how to integrate more affordable ART options into existing infrastructures.

中文翻译：

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低收入和中等收入国家的体外受精和其他辅助生殖技术：系统的景观分析

不孕症影响着全世界 4850 万对夫妇，低收入和中等收入国家 (LMIC) 的患病率估计为 3.5-16.7%，撒哈拉以南非洲地区的患病率高达 30-40%。由于治疗费用高昂以及文化、宗教和法律障碍，大多数不孕夫妇无法获得抗逆转录病毒治疗服务。不孕不育和无子女现象，特别是在中低收入国家，会造成毁灭性的后果，这引起了人们对开发负担得起的体外受精程序的极大兴趣。然而，关于在不同现场条件下复制技术的安全性、效率和能力，以及如何将更实惠的 ART 选项整合到现有基础设施中的证据很少。