Abstract

The ability of alkalophilic micromycetes of the species Sodiomyces alkalinus to produce antimicrobial compounds was studied. As a result of the determination of the spectrum and yield of antibiotic compounds, a promising producer of the antimycotics Sodiomyces alkalinus was selected from the most active strains 8KS17-10. The producer exhibited antifungal activity against opportunistic fungi, as well as pathogenic clinical isolates of molds and yeasts—pathogens of systemic mycoses. The isolated active compound can be attributed to the group of antimicrobial glycopeptides based on the totality of the identified structural features (molecular weight, absorption ratio at certain wavelengths).

中文翻译：

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嗜碱真菌Sodiomyces hydronus的抗菌潜力和菌株的选择-新型抗微生物化合物的生产

摘要

研究了嗜碱菌（Sodiomyces basicnus）种的嗜碱微真菌产生抗菌化合物的能力。确定抗生素化合物的谱图和收率的结果是，从活性最高的菌株8KS17-10中选择了有希望的抗真菌剂Sodiomyces hydronus的生产者。生产者表现出对机会性真菌以及霉菌和酵母的致病性临床分离株（系统性霉菌病的病原体）的抗真菌活性。基于所鉴定的结构特征（分子量，在某些波长下的吸收率）的总和，可以将分离的活性化合物归为抗微生物糖肽的组。