Abstract

We have explored the use of (diethoxymethyl)benzaldehyde readily available as a starting material allowing us to end up with Terpyridinebenzaldehyde isomers. An environmentally friendly procedure was undertaken for the synthesis of a series of 4, 3 and 2-([2,2′:6′,2″-terpyridin]-4′-yl)benzaldehyde isomers (para, meta and ortho position). These compounds have been synthesized in one-pot conditions using ethanol and aqueous ammonia as solvents, at room temperature. This methodology offers substantial advantages with respect to its simplicity of operation, reaction time, satisfying yield of products and easy work-up procedure under mild reaction conditions. Apart from spectroscopic characterization, the structure of one of the Terpyridinebenzaldehyde derivative is confirmed by single-crystal X-ray diffraction.

摘要

我们已经探索了容易使用的（二乙氧基甲基）苯甲醛作为起始原料的应用，使我们最终可以得到叔吡啶苯甲醛异构体。进行了环境友好的程序，用于合成一系列4、3和2-（[[2,2'：6'，2''-terpyridin] -4'-yl）苯甲醛异构体（对位，间位和邻位）位置）。在室温下，使用乙醇和氨水作为溶剂，在一锅条件下合成了这些化合物。该方法就其操作简单，反应时间，令人满意的产物收率和在温和的反应条件下易于后处理程序方面而言，具有实质性的优势。除光谱表征外，通过单晶X射线衍射证实了一种吡啶基苯甲醛衍生物的结构。