Abstract

Juvenile granulosa cell tumor (JGCT) is the most common type of sex cord stromal tumor arising from gonadal structures of children and young adults. We present a 3.5-year-old girl with JGCT located in retroperitoneum without ovarian involvement. Extragonadal occurrences of other sex cord stromal tumors have been rarely reported, but this is the first case of JGCT in an extragonadal location. We speculate the possible underlying mechanism of sex cord stromal tumor formation in extragonadal locations. Furthermore, clinical presentation, differential diagnosis and management of this tumor in childhood are discussed.

中文翻译：

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青春期前儿童的卵巢外少年颗粒细胞瘤：一种罕见肿瘤的新位置

摘要

少年颗粒细胞瘤（JGCT）是性索间质肿瘤的最常见类型，其起源于儿童和年轻人的性腺结构。我们介绍了一个3.5岁的女孩，她的JGCT位于腹膜后，没有卵巢受累。很少有其他性索间质肿瘤在性腺外发生的报道，但这是JGCT在性腺外位置的首例病例。我们推测性腺外部位性索间质肿瘤形成的潜在机制。此外，讨论了儿童期该肿瘤的临床表现，鉴别诊断和治疗。