Research on placebo analgesia commonly focuses on the impact of information about direction (i.e., increase or decrease of pain) and magnitude of the expected analgesic effect, whereas temporal aspects of expectations have received little attention so far. In a recent study, using short-lasting, low-intensity stimuli, we demonstrated that placebo analgesia onset is influenced by temporal information. Here, we investigate whether the same effect of temporal suggestions can be found in longer lasting, high-intensity pain in a Cold Pressor Test (CPT).

中文翻译：

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持续疼痛实验模型中安慰剂镇痛的“外部时间”

安慰剂镇痛的研究通常集中在有关方向（即疼痛的增加或减少）和预期镇痛效果大小的信息的影响上，而预期的时间方面迄今为止很少受到关注。在最近的一项研究中，使用短时、低强度的刺激，我们证明了安慰剂镇痛的起效受时间信息的影响。在这里，我们调查是否可以在冷加压测试 (CPT) 中的更持久、高强度疼痛中发现时间建议的相同效果。