Monocrotophos (MCP) is an organophosphate insecticide with broad application in agricultural crops like rice, maize, sugarcane, cotton, soybeans, groundnut and vegetables. MCP solubilize in water readily and thus reduced sorption occurs in soil. This leads to MCP leaching into the groundwater and pose a significant threat of contamination. The MCP’s half-life depends on the temperature and pH value and estimated as 17–96 d. But the half-life of technical grade MCP can exceed up to 2500 days if properly stored at 38 °C in a glass or polyethylene container in a stable condition. It causes abnormality, ranging from mild to severe confusion, agitation, hypersalivation, convulsion, pulmonary failure, senescence in mammals and insects. MCP affects humans by inhibiting the activity of the acetylcholine esterase enzyme. MCP is accountable for the catalytic degradation of acetylcholine and affects the neurotransmission between neurons. This review discusses MCP’s various aspects and fate on aquatic and terrestrial life forms, quantification methods for monitoring, various degradation processes, and their mechanisms. Different case studies related to its impact on the human population in different parts of the world have been discussed. Efforts have also been made to summarize and present different microbial population’s role in its degradation and mineralization.

久效磷（MCP）是一种有机磷酸盐杀虫剂，广泛用于农业作物，如水稻，玉米，甘蔗，棉花，大豆，花生和蔬菜。MCP易溶于水，因此在土壤中的吸附减少。这导致MCP渗入地下水，并带来严重的污染威胁。MCP的半衰期取决于温度和pH值，估计为17-96 d。但是，如果将MCP技术等级的MCP稳定地在38°C的玻璃或聚乙烯容器中正确存放，其半衰期可能会超过2500天。它引起异常，范围从轻度到严重的混乱，躁动，唾液分泌过多，抽搐，肺衰竭，哺乳动物和昆虫的衰老。MCP通过抑制乙酰胆碱酯酶的活性来影响人类。MCP负责乙酰胆碱的催化降解并影响神经元之间的神经传递。这篇评论讨论了MCP的各个方面以及关于水生和陆地生命形式，监测的量化方法，各种降解过程及其机理的命运。已经讨论了有关其对世界不同地区人口的影响的不同案例研究。还努力总结并介绍了不同微生物种群在其降解和矿化中的作用。讨论了有关其对世界不同地区人口的影响的不同案例研究。还努力总结并介绍了不同微生物种群在其降解和矿化中的作用。已经讨论了有关其对世界不同地区人口的影响的不同案例研究。还努力总结并介绍了不同微生物种群在其降解和矿化中的作用。