Chronic diseases can greatly benefit from bioelectronic medicine approaches. Neuromorphic electronic circuits present ideal characteristics for the development of brain-inspired low-power implantable processing systems that can be interfaced with biological systems. These circuits, therefore, represent a promising additional tool in the tool-set of bioelectronic medicine. In this paper, we describe the main features of neuromorphic circuits that are ideally suited for continuously monitoring the physiological parameters of the body and interact with them in real-time. We propose examples of computational primitives that can be used for real-time pattern generation and present a neuromorphic implementation of neural oscillators for the generation of sequence activation patterns. We demonstrate the features of such systems with an implementation of a three-phase network that models the dynamics of the respiratory Central Pattern Generator (CPG) and the heart chambers rhythm, and that could be used to build an adaptive pacemaker.

中文翻译：

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生物电子医学的神经形态模式生成电路

慢性疾病可以大大受益于生物电子医学方法。神经形态电子电路为开发可与生物系统连接的大脑启发型低功率可植入处理系统提供了理想的特性。因此，这些电路代表了生物电子医学工具集中的一种有前途的附加工具。在本文中，我们描述了神经形态电路的主要特征，它们非常适合连续监测人体的生理参数并与之实时交互。我们提出了可用于实时模式生成的计算原语示例，并提出了用于生成序列激活模式的神经振荡器的神经形态实现。