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Pterostilbene accelerates wound healing by modulating diabetes-induced estrogen receptor β suppression in hematopoietic stem cells
Burns & Trauma ( IF 6.3 ) Pub Date : 2021-02-22 , DOI: 10.1093/burnst/tkaa045
Weiguo Xie 1 , Xueqing Zhou 1 , Weigang Hu 1 , Zhigang Chu 1 , Qiongfang Ruan 1 , Haimou Zhang 2 , Min Li 1 , Hongyu Zhang 3 , Xiaodong Huang 1 , Paul Yao 1
Affiliation  

Delayed wound healing is one of the major complications of diabetes mellitus and is characterized by prolonged inflammation, delayed re-epithelialization and consistent oxidative stress, although the detailed mechanism remains unknown. In this study, we aimed to investigate the potential role and effect of pterostilbene (PTE) and hematopoietic stem cells (HSCs) on diabetic wound healing.

中文翻译:

紫檀芪通过调节糖尿病诱导的造血干细胞中雌激素受体β抑制来加速伤口愈合

伤口愈合延迟是糖尿病的主要并发症之一,其特点是炎症延长、上皮再形成延迟和持续的氧化应激,但详细机制仍不清楚。在这项研究中,我们旨在研究紫檀芪 (PTE) 和造血干细胞 (HSC) 在糖尿病伤口愈合中的潜在作用和影响。
更新日期:2021-02-22
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