The possibility of removing tetracycline (TRC) from water in an integrated advanced oxidation and membrane filtration process was investigated. Ozonation and UV/H₂O₂ photooxidation were applied for the destruction of TRC. Six oxidation products (OPs) retaining the structural core of TRC have been identified. One new TRC oxidation product, not reported so far in the literature, was identified—ethyl 4-ethoxybenzoate. All identified OPs were effectively retained on the membrane in the nanofiltration process. However, chemical oxygen demand (COD) measurements of the filtrates showed that in the case of UV/H₂O₂ oxidation, the OPs passed through the membrane into the filtrate. Various water matrices were used in the research, including the river water untreated and after ozone treatment. It has been shown that organic matter present in surface water can improve pharmaceutical retention, although it contributes to significant membrane fouling. Pre-ozonation of the river water reduced the membrane fouling. The XPS analysis was used to show ozone and H₂O₂ influence on the top polymer layer of the membrane. It was shown that the oxidants can damage the amide bond of the polyamide.

中文翻译：

---

在纳滤过程中去除四环素氧化产物

研究了在集成的高级氧化和膜过滤过程中从水中去除四环素（TRC）的可能性。将臭氧和UV / H ₂ O ₂光氧化作用用于破坏TRC。已经确定了六个保留TRC结构核心的氧化产物（OPs）。鉴定出一种新的TRC氧化产物，至今尚未在文献中报道，是4-乙氧基苯甲酸乙酯。在纳米过滤过程中，所有鉴定出的OP有效地保留在膜上。但是，对滤液的化学需氧量（COD）测量表明，在UV / H ₂ O ₂的情况下氧化，OPs通过膜进入滤液。研究中使用了各种水基质，包括未经处理和经过臭氧处理的河水。研究表明，地表水中存在的有机物虽然可以显着改善膜的结垢，但可以改善药物的保留能力。河水的预臭氧化作用减少了膜的结垢。XPS分析用于显示臭氧和H ₂ O ₂对膜的顶部聚合物层的影响。结果表明，氧化剂会破坏聚酰胺的酰胺键。