ABSTRACT

Objectives

The aim of the study was to determine the effects of two different types of single cardiac rehabilitation (CR) exercise modes on the inflammation status, oxidative stress and total antioxidant capacity (TAC) of saliva.

Methods

The study involved two groups of CR patients: group A (n = 21) used a cycloergometer, and group B (n = 21) received breathing and balance exercises. C-reactive protein as an inflammatory biomarker, malondialdehyde (MDA) as a measure of the level of oxidative stress and salivary 2.2-diphenyl-1-picryl-hydrazyl (DPPH) as an index of TAC were performed twice: before the beginning of the CR exercise (pre-CR) and immediately after (post-CR).

Results

No significant changes were observed for the inflammatory response of saliva after CR exercise regardless of its type. MDA decreased (pre-CR: 39.7 ± 101.9 vs. post-CR: 16.8 ± 44.3 ng·mL⁻¹; p < 0.01) and DPPH increased (pre-CR: 25.9 ± 16.7 vs. post-CR: 32.6 ± 14.0% reduction; p < 0.05) after CR exercise in the group B, with similar but not statistically significant changes in the group A.

Discussion

Two popular exercise modes, especially breathing and balance exercises, reduce salivary oxidative stress and enhance the antioxidant potential of saliva in CR patients. The approval of saliva as a non-invasive source of information about inflammation status, oxidative stress and antioxidant capacity in cardiac patients requires further studies.

中文翻译：

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两种不同类型的单一运动模式对心肌梗死后患者唾液C反应蛋白浓度、氧化应激和抗氧化能力的影响

摘要

目标

该研究的目的是确定两种不同类型的单一心脏康复 (CR) 运动模式对唾液的炎症状态、氧化应激和总抗氧化能力 (TAC) 的影响。

方法

该研究涉及两组 CR 患者：A 组（n  = 21）使用循环测力计，B 组（n  = 21）接受呼吸和平衡练习。C反应蛋白作为炎症生物标志物，丙二醛（MDA）作为氧化应激水平的量度和唾液2.2-二苯基-1-苦基-肼（DPPH）作为TAC的指标进行了两次：在开始之前CR 练习（前 CR）和紧接后（后 CR）。

结果

CR运动后唾液的炎症反应，无论其类型如何，均未观察到显着变化。MDA 下降（CR 前：39.7 ± 101.9 对比 CR 后：16.8 ± 44.3 ng·mL ^-1；p  < 0.01）和 DPPH 增加（CR 前：25.9 ± 16.7 对比 CR 后：32.6 ± 14.0%减少；p  < 0.05) B 组 CR 运动后，A 组变化相似但无统计学意义。

讨论

两种流行的运动模式，尤其是呼吸和平衡运动，可以减少 CR 患者的唾液氧化应激，增强唾液的抗氧化能力。批准唾液作为关于心脏病患者炎症状态、氧化应激和抗氧化能力的非侵入性信息来源需要进一步研究。