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Feasibility study of radiophotoluminescent glass dosimeter for in vivo dosimetry in external photon beam radiotherapy
Journal of the Korean Physical Society ( IF 0.8 ) Pub Date : 2021-02-22 , DOI: 10.1007/s40042-021-00092-4
Nazia Neelam Shehzadi , Chul-Young Yi , Ki-Hwan Kim , Jaeuk Jang , Ui-Jung Hwang , Yunho Kim , In Jung Kim , Young Min Seong

The purpose of this study was to check the applicability of radiophotoluminescent glass dosimeter (RPLGD) for in vivo dosimetry in external photon beams radiotherapy. The entrance dose measurements were performed. The influence of beam set-up parameters on the entrance dose was investigated using the RPLGDs. In this study, the RPLGD and 6-MV photon beam produced by a linear accelerator were used. The entrance dose calibration factors of the RPLGDs and beam energy and geometry-dependent correction factors were measured using a water phantom. For a correction factor related to the irradiation set-up, Monte Carlo (MC) simulation was performed. The entrance dose verification was performed on an Alderson Rando phantom during 64 single beam irradiations using different beam set-up. One RPLGD was attached on surface during a single beam irradiation for delivery of clinically planned dose. Additionally, during 50 irradiations, one RPLGD was placed directly inside the Alderson Rando phantom at different points in the beam path to verify the dose delivery. The mean ratio of the measured entrance dose using RPLGD on the surface of the phantom to the expected dose which was calculated by treatment planning system was equal to 1.001 ± 0.030. The mean ratio of the dose measured using RPLGDs inside the Alderson Rando phantom to the expected dose was equal to 1.019 ± 0.019. This study concludes that the RPLGD is suitable for in vivo dosimetry in external photon beam radiotherapy for dose verification within ± 5% at the clinically acceptable level.



中文翻译:

放射光致发光玻璃剂量计在体外光子束放射治疗中体内剂量测定的可行性研究

这项研究的目的是检查放射光致发光玻璃剂量计(RPLGD)在外部光子束放射治疗中进行体内剂量测定的适用性。进行入口剂量测量。使用RPLGDs研究了光束设置参数对入射剂量的影响。在这项研究中,使用了线性加速器产生的RPLGD和6-MV光子束。RPLGDs的入射剂量校准因子以及束能量和几何形状相关的校正因子是使用水体模测量的。对于与辐照设置有关的校正因子,执行了蒙特卡洛(MC)模拟。使用不同的光束设置,在64次单光束辐照期间,对Alderson Rando体模进行了入射剂量验证。在单束照射过程中将一个RPLGD附着在表面上,以递送临床计划剂量。此外,在50次照射期间,将一个RPLGD直接放置在Alderson Rando体模内的光束路径的不同点处,以验证剂量传递。使用治疗计划系统计算的幻影表面上使用RPLGD测得的入场剂量与预期剂量的平均比率等于1.001±0.030。使用Alderson Rando幻影内部的RPLGD测量的剂量与预期剂量的平均比等于1.019±0.019。这项研究得出的结论是,RPLGD适用于外部光子束放射治疗的体内剂量测定,以在临床可接受的水平上将剂量验证在±5%之内。将一个RPLGD直接放在Alderson Rando体模内的光束路径上的不同点以验证剂量传递。使用治疗计划系统计算的幻影表面上使用RPLGD测得的入场剂量与预期剂量的平均比率等于1.001±0.030。使用Alderson Rando幻影内部的RPLGD测量的剂量与预期剂量的平均比等于1.019±0.019。这项研究得出的结论是,RPLGD适用于外部光子束放射治疗的体内剂量测定,以在临床可接受的水平上将剂量验证在±5%之内。将一个RPLGD直接放在Alderson Rando体模内的光束路径上的不同点以验证剂量传递。使用治疗计划系统计算的幻影表面上使用RPLGD测得的入场剂量与预期剂量的平均比率等于1.001±0.030。使用Alderson Rando幻影内部的RPLGD测量的剂量与预期剂量的平均比等于1.019±0.019。这项研究得出的结论是,RPLGD适用于外部光子束放射治疗的体内剂量测定,以在临床可接受的水平上将剂量验证在±5%之内。使用治疗计划系统计算的幻影表面上使用RPLGD测得的入场剂量与预期剂量的平均比率等于1.001±0.030。使用Alderson Rando幻影内部的RPLGD测量的剂量与预期剂量的平均比等于1.019±0.019。这项研究得出的结论是,RPLGD适用于外部光子束放射治疗的体内剂量测定,以在临床可接受的水平上将剂量验证在±5%之内。使用治疗计划系统计算的幻影表面上使用RPLGD测得的入场剂量与预期剂量的平均比等于1.001±0.030。使用Alderson Rando幻影内部的RPLGD测量的剂量与预期剂量的平均比等于1.019±0.019。这项研究得出的结论是,RPLGD适用于外部光子束放射治疗的体内剂量测定,以在临床可接受的水平上将剂量验证在±5%之内。

更新日期:2021-02-22
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