Scaffolds are very important element for bone regeneration issues. On this way, the purpose of this paper is the design and manufacturing of porous scaffolds fabricated by 3D printing technology from biodegradable thermoplastic polymers and calcium phosphates (in micrometric scale). So, the main aim of this research is to obtain complex porous 3D structures that present adequate mechanical properties in relation to bones, through a structured interconnectivity between the pores. Based on the 3D models of the designed scaffolds, selection and preparation of the biomaterials, the process parameters were set in order to provide conditions for the scaffolds’ manufacturing. Using an additive manufacturing technology of pneumatic gelling liquid extrusion, with a bioprinter that uses pneumatic distribution system for continuous extrusion of material, two models of designed scaffolds were 3D printed and characterized by mechanical compression analyses and then, evaluated by Scanning Electron Microscopy (SEM) method. Results of Linear Static Analysis (LSA) showed that the 3D designed scaffolds meet the specifications required in the literature for specific rigidity (20–141 MPa). The stress x strain curves showed that the compressive strength values of the composite biomaterial used for all tested coupons are within the values described in the literature for trabecular bone application (range from 2 to 12 MPa). In addition, the pore sizes proven by micrographs have been within the range of application for tissue engineering (20–850 μm), as mentioned by the literature too. Also, the SEM showed the repeatability related to the interconnectivity between pores, based on homogeneous and uniform structures, regarding adhesion between layers, dimensions of pores and constant extruded filament. Thus, development and applications of the biomaterial composed by Polycaprolactone and Amorphous Calcium Phosphate (PCL + ACP) faced to the additive manufacturing method used to perform the printing of designed scaffolds, can be considered a potential and promising novelty for application in tissue engineering field.

支架是骨骼再生问题中非常重要的元素。通过这种方式，本文的目的是设计和制造通过3D打印技术由可生物降解的热塑性聚合物和磷酸钙（微米级）制造的多孔支架。因此，这项研究的主要目的是通过孔之间的结构互连来获得呈现出与骨骼相关的足够机械性能的复杂多孔3D结构。基于所设计支架的3D模型，生物材料的选择和制备，设置了工艺参数，以便为支架的制造提供条件。利用气动胶凝液体挤​​出的增材制造技术，以及使用气动分配系统连续挤出材料的生物打印机，3D打印设计的支架的两个模型并通过机械压缩分析进行表征，然后通过扫描电子显微镜（SEM）方法进行评估。线性静态分析（LSA）的结果表明，经3D设计的脚手架符合文献中对特定刚度（20-141 MPa）的要求。应力x应变曲线表明，用于所有测试样板的复合生物材料的抗压强度值均在小梁骨应用文献中描述的值范围内（2到12 MPa）。此外，正如文献所提到的那样，通过显微照片证实的孔径已在组织工程应用范围内（20–850μm）。此外，SEM还显示了与孔之间的互连性相关的可重复性，基于均匀和均匀的结构，涉及层之间的粘附力，孔的尺寸和恒定挤出的长丝。因此，聚己内酯和无定形磷酸钙（PCL + ACP）组成的生物材料的开发和应用面临着用于执行设计支架的印刷的增材制造方法，可以认为是在组织工程领域中应用的潜在和有希望的新颖性。