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Investigating the Clinical Utility of the Combined Use of Objective and Subjective Measures of ADHD During Treatment Optimization
Journal of Clinical Psychopharmacology ( IF 2.9 ) Pub Date : 2022-03-01 , DOI: 10.1097/jcp.0000000000001350
Nayra A Martin-Key 1 , Amy Stevenson 2 , Perry Roy 3
Affiliation  

Background 

This study investigated the clinical utility of the combined use of objective and subjective measures of attention-deficit/hyperactivity disorder (ADHD) prepharmacological and postpharmacological treatment.

Methods 

Adults with ADHD (N = 77) completed the Quantified Behavioral Test, self-ratings of ADHD-related symptoms, and quality of life measures pretreatment and posttreatment.

Results 

The use of objective and subjective measures of ADHD-related symptoms during initiation and follow-up of pharmacological treatment resulted in significant improvements in quality of life after 6 months. Both objective and subjective measures captured changes in ADHD-related symptoms, with more patients showing clinically relevant treatment effects on objective measures. Convergence rates between objective and subjective measures were low to moderate, and improvements on these measures correlated with increased quality of life.

Conclusions 

Objective and subjective measures of ADHD capture important components of the condition. The findings from this study have important implications for clinical practice.



中文翻译:


研究在优化治疗过程中结合使用 ADHD 客观和主观测量的临床效用


 背景


本研究调查了注意力缺陷/多动障碍(ADHD)药前和药后治疗联合使用客观和主观措施的临床效用。

 方法


患有 ADHD 的成年人 (N = 77) 完成了量化行为测试、ADHD 相关症状的自我评估以及治疗前和治疗后的生活质量测量。

 结果


在药物治疗开始和随访期间对 ADHD 相关症状进行客观和主观测量,6 个月后生活质量显着改善。客观和主观测量都捕捉到了多动症相关症状的变化,更多的患者在客观测量上表现出临床相关的治疗效果。客观和主观测量之间的收敛率较低至中等,这些测量的改善与生活质量的提高相关。

 结论


ADHD 的客观和主观测量捕捉了该病症的重要组成部分。这项研究的结果对临床实践具有重要意义。

更新日期:2022-03-01
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