A Fucoxanthinol Induces Apoptosis in a Pancreatic Intraepithelial Neoplasia Cell.,Cancer Genomics & Proteomics

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A Fucoxanthinol Induces Apoptosis in a Pancreatic Intraepithelial Neoplasia Cell.
Cancer Genomics & Proteomics ( IF 2.6 ) Pub Date : 2021-2-21 , DOI: 10.21873/cgp.20248
Masaru Terasaki _{1,

2} , Takuya Inoue ₃ , Wataru Murase ₃ , Atsuhito Kubota ₃ , Hiroyuki Kojima _{2,

3} , Mareshige Kojoma ₃ , Tohru Ohta ₂ , Hayato Maeda ₄ , Kazuo Miyashita ₅ , Michihiro Mutoh ₆ , Mami Takahashi ₇

Affiliation

Fucoxanthinol (FxOH), a predominant metabolite from fucoxanthin (Fx), can exert potential anti-cancer effects in various cancers. However, limited data are available on the effect of FxOH or Fx on pancreatic cancer. The present study investigated the effect of FxOH on a cell line derived from pancreatic cancer tissue developed in Ptf1a^Cre/+; LSL-k-ras^G12D/+ mice.

中文翻译：

岩藻黄醇诱导胰腺上皮内瘤变细胞凋亡。

岩藻黄质醇 (FxOH) 是岩藻黄质 (Fx) 的主要代谢产物，可在多种癌症中发挥潜在的抗癌作用。然而，关于 FxOH 或 Fx 对胰腺癌的影响的数据有限。本研究调查了 FxOH 对源自 Ptf1a ^Cre/+中开发的胰腺癌组织的细胞系的影响； LSL-k-ras ^G12D/+小鼠。

更新日期：2021-02-22

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