Silver nanoparticle driven signal amplification for electrochemical chiral discrimination of amino acids,Analyst

当前位置： X-MOL 学术 › Analyst › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Silver nanoparticle driven signal amplification for electrochemical chiral discrimination of amino acids
Analyst ( IF 3.6 ) Pub Date : 2021-2-6 , DOI: 10.1039/d1an00119a
Shanshan Wu _{1,

2,

3,

4} , Hui Wang _{1,

2,

3,

4} , Datong Wu _{1,

2,

3,

4} , Gao-Chao Fan _{5,

6,

7,

8,

9} , Yongxin Tao _{1,

2,

3,

4} , Yong Kong _{1,

2,

3,

4}

Affiliation

β-Cyclodextrin (β-CD) modified silver nanoparticles (AgNPs), denoted as β-CD/AgNPs, were prepared by a simple one-pot method. Due to the inherent chirality of β-CD, the developed β-CD/AgNPs exhibited higher affinity toward L-tyrosine (L-Tyr) than D-tyrosine (D-Tyr), leading to serious aggregation of AgNPs in the presence of L-Tyr. Consequently, the L-Tyr induced aggregation of AgNPs can result in signal amplification in the differential pulse voltammograms (DPVs) of L-Tyr, which can be applied for the electrochemical chiral discrimination of the Tyr enantiomers. Other chiral amino acids including tryptophan and phenylalanine can also be successfully discriminated with the β-CD/AgNPs, suggesting high universality of the developed chiral sensor.

中文翻译：

银纳米粒子驱动的信号放大，用于氨基酸的电化学手性鉴别

通过简单的一锅法制备了β-环糊精（β-CD）修饰的银纳米颗粒（AgNPs），称为β-CD/ AgNPs。由于β-CD，将显影的β-CD的固有的手性/表现的AgNPs朝向更高的亲和力大号-酪氨酸（大号-Tyr）比d -酪氨酸（d -Tyr），导致的AgNPs的严重聚集在存在大号蒂尔因此，大号的AgNPs的-Tyr诱导的聚集可导致信号放大中的微分脉冲伏安图（DPVS）大号-Tyr，可用于Tyr对映异构体的电化学手性鉴别。其他手性氨基酸（包括色氨酸和苯丙氨酸）也可以用β-CD/ AgNPs进行成功区分，这表明已开发的手性传感器具有很高的通用性。

更新日期：2021-02-19

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11