Background: In neuroendocrine tumor (NET), complete surgery could better the prognosis. Radioguided surgery (RGS) with β⁻-radioisotopes is a novel approach focused on developing a new probe that, detecting electrons and operating with low background, provides a clearer delineation of the lesions with low radiation exposition for surgeons. As a first step to validate this procedure, ex vivo specimens of tumors expressing somatostatin receptors, as small intestine neuroendocrine tumor (SI-NET), were tested.

中文翻译：

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使用 90Y-DOTATOC 在小肠神经内分泌肿瘤中进行 β--放射引导手术的首次体外结果

背景：在神经内分泌肿瘤（NET）中，完整的手术可以更好地预后。使用 β ^-放射性同位素的放射引导手术 (RGS)是一种专注于开发新探针的新方法，该探针可检测电子并在低背景下操作，为外科医生提供更清晰的病变轮廓，同时低辐射暴露。作为验证该程序的第一步，测试了表达生长抑素受体的肿瘤的离体标本，如小肠神经内分泌肿瘤 (SI-NET)。