Abstract

Purpose

Limb amputation is a life-altering procedure used to treat certain cancer patients. The influence of psychosocial factors (such as marital status) on outcomes is poorly understood, hindering the development of targeted resources for the specific needs of these patients. This study was conducted to characterize the influence of marital status on survival after cancer-related amputation.

Design/Research Approach

Retrospective cohort study.

Sample

1,516 patients with cancer-related amputation were studied from the Surveillance, Epidemiology and End Results database.

Methods

Patients were grouped by marital status as single, married or divorced/separated/widowed and survival was compared using multivariate cox regression adjusted for demographic, tumor and treatment factors.

Findings

Adjusted analysis showed that single (HR, 1.213; p = .044) patients had a significantly higher overall mortality-risk, while divorced/separated/widowed patients had both a significantly higher overall (HR, 1.397; p < .001) and cause-specific mortality-risk (HR, 1.381; p = .003) compared to married patients.

Conclusion

We posit that the increased psychosocial support available to married cancer patients may play a key role in improving survival.

Implications for Psychosocial Providers

These findings provide new insight about the psychosocial needs of cancer amputees and the prognostic implications for those lacking social support of a spouse.

中文翻译：

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基于婚姻状况的癌症截肢者生存率差异：对监测、流行病学和最终结果 (SEER) 数据库的分析

摘要

目的

截肢是一种改变生命的手术，用于治疗某些癌症患者。人们对心理社会因素（如婚姻状况）对结果的影响知之甚少，阻碍了针对这些患者的特定需求开发有针对性的资源。本研究旨在描述婚姻状况对癌症相关截肢后生存率的影响。

设计/研究方法

回顾性队列研究。

样本

从监测、流行病学和最终结果数据库中研究了 1,516 名癌症相关截肢患者。

方法

患者按婚姻状况分为单身、已婚或离婚/分居/丧偶，并使用针对人口统计学、肿瘤和治疗因素调整的多变量 cox 回归比较生存率。

发现

调整后的分析显示，单身（HR，1.213；p = .044）患者的总体死亡风险显着更高，而离婚/分居/丧偶患者的总体死亡风险（HR，1.397；p < .001）和原因均显着更高。 -与已婚患者相比，特定的死亡风险（HR，1.381；p = .003）。

结论

我们假设已婚癌症患者可获得的增加的社会心理支持可能在提高生存率方面发挥关键作用。

对社会心理提供者的影响

这些发现为癌症截肢者的心理社会需求以及对那些缺乏配偶社会支持的人的预后影响提供了新的见解。