Naproxen (NPX), one of the representative non-steroidal anti-inflammatory drug (NSAID) ingredients, was decomposed by plasma in liquid process (PiLP). Strongly oxidized species generated in the plasma field of the PiLP, such as OH radicals, were confirmed by optical emission spectroscopy Increasing the operation parameters (pulse width, frequency and applied voltage) of the power supply promoted plasma field generation and OH radical generation, and affected the NPX decomposition rate. Although the NPX decomposition reaction rate was improved by up to 18 ∼ 30% by adding TiO₂ photocatalyst powder and H₂O₂ to PiLP, but the optimal addition amount should be determined considering the plasma generation and scavenger effects. A decomposition pathway was proposed, in which NPX was mineralized into CO₂ and H₂O through five intermediates mainly by decarboxylation, demethylation, hydroxylation, and dehydration reactions via hydroxyl radicals.

萘普生（NPX）是代表性的非甾体抗炎药（NSAID）成分之一，在血浆中被液化（PiLP）分解。通过光发射光谱法确认了在PiLP的等离子体场中产生的强氧化物质（例如OH自由基）。增加电源的操作参数（脉冲宽度，频率和施加电压）会促进等离子体场的产生和OH自由基的产生，并且影响了NPX的分解速率。尽管通过添加TiO ₂光催化剂粉末和H ₂ O _2可以将NPX分解反应速率提高18％到30％。对于PiLP，最好的添加量应考虑血浆生成和清除剂的影响来确定。甲分解途径被提出，其中NPX被矿化成CO ₂和H ₂通过羟基自由基ö通过五个中间体主要由脱羧，脱甲基化，羟基化，和脱水反应。