Background

A range of myopia management (MM) contact lenses are becoming available to practitioners. These lenses are designed to slow myopia progression and axial elongation. This study explored the initial experience of participants wearing daily disposable MM contact lenses to investigate established factors previously associated with successful lens wear.

Methods

This was a prospective, double-masked, crossover study. Twenty participants aged 18–30 years old were assigned to wear two daily disposable MM lenses in a randomised order. Visual acuity, contrast sensitivity, and amplitude/lag of accommodation were assessed at baseline, post-insertion, and after 2 and 6 h of lens wear. Self-reported lens comfort and vision quality were recorded at the same timepoints, and at 10 h post-insertion. Pairwise comparisons were performed between the two lenses at each timepoint, as well as assessing changes throughout wear. The relationship of the measured parameters to overall lens satisfaction was also assessed.

Results

There were no significant differences between the two MM lenses at any timepoint for any of the participant-reported parameters, including overall satisfaction. A small difference in visual acuity was noted at 6 h post-insertion, although this is unlikely to be clinically significant. Comfort decreased throughout the day, most notably at 10 h post-insertion. A moderate positive correlation was observed between participant-reported visual quality and overall satisfaction. A similar pattern was seen for comfort and overall satisfaction. Self-reported vision quality and measured visual acuity were poorly correlated, highlighting the benefit of subjectively assessing the quality of vision with these lenses.

Conclusions

The participants demonstrated comparable measures across a range of measures between the two MM lenses. Notably, half of the participants demonstrated a clear lens preference, although the preferred lens varied between individuals. Candidates for MM may benefit from trialling more than one MM lens design, to maximise initial wearing satisfaction.

中文翻译：

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两种市售日抛型近视控制隐形眼镜的患者体验和生理反应

背景

从业者可以使用一系列近视管理 (MM) 隐形眼镜。这些镜片旨在减缓近视发展和轴向伸长。本研究探讨了参与者佩戴日抛型 MM 隐形眼镜的初步体验，以调查先前与成功佩戴隐形眼镜相关的既定因素。

方法

这是一项前瞻性、双盲、交叉研究。20 名 18-30 岁的参与者被分配以随机顺序佩戴两个日抛 MM 镜片。在基线、插入后以及镜片佩戴 2 小时和 6 小时后评估视力、对比敏感度和调节幅度/滞后。在相同时间点和插入后 10 小时记录自我报告的镜片舒适度和视力质量。在每个时间点对两个镜片进行成对比较，并评估整个佩戴过程中的变化。还评估了测量参数与整体镜片满意度的关系。

结果

对于参与者报告的任何参数，包括总体满意度，两个 MM 镜片在任何时间点都没有显着差异。在插入后 6 小时观察到视力的微小差异，尽管这不太可能具有临床意义。全天舒适度下降，最明显的是在插入后 10 小时。在参与者报告的视觉质量和总体满意度之间观察到中度正相关。在舒适度和整体满意度方面也看到了类似的模式。自我报告的视力质量和测量的视力相关性较差，突出了使用这些镜片主观评估视力质量的好处。

结论

参与者在两个 MM 镜片之间的一系列测量中展示了可比较的测量。值得注意的是，一半的参与者表现出明显的镜片偏好，尽管偏好的镜片因人而异。MM 的候选人可能会从尝试一种以上的 MM 镜片设计中受益，以最大限度地提高初始佩戴满意度。