Purpose The management of sexual offending is a major challenge, particularly in men who have an intellectual disability. Psychological therapies have been shown beneficial, and programmes designed for use in the general population have been adapted for use in offenders who have an intellectual disability. There is also a role for pharmacological management, although the quality of evidence for this is noticeably lacking, most likely associated with the ethical and legal issues encountered in conducting well designed and controlled trials in this area. The purpose of this paper is to look at the pharmacological management options available. Design/methodology/approach A literature search of electronic databases was undertaken. Additionally, the references lists for identified papers were examined for any further relevant publications. Findings The two main categories of drugs used in the management of inappropriate sexual behaviour are the testosterone-lowering drugs and the psychotropic drugs. Most trials were open and utilised self-report measures of drug effectiveness, limiting their usefulness. Most trials noted beneficial effect. Side effect profiles and patient adherence can limit the effectiveness of anti-libidinal medication in practice. Originality/value There is very limited evidence available for the use of pharmacological agents in the management of inappropriate sexual behaviour, owing to the lack of adequately controlled clinical trials. New studies are therefore required, particularly of larger sample sizes, longer durations, and examining characteristics of those who benefit from pharmacological treatment, although the ethical issues of conducting such studies is duly acknowledged.

中文翻译：

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学习障碍者性犯罪行为的药理管理研究述评

目的管理性犯罪是一项重大挑战，尤其是在智障男性中。心理疗法已被证明是有益的，专为普通人群设计的程序已被改编为适合智障者使用。尽管明显缺乏证据质量，但药理学管理也有作用，这很可能与在该领域进行精心设计和控制的试验中遇到的道德和法律问题有关。本文的目的是研究可用的药理管理选项。设计/方法/方法进行了电子数据库的文献检索。此外，还检查了已鉴定论文的参考文献清单，以查找任何其他相关出版物。研究结果用于管理不当性行为的药物的两大类是降低睾丸激素的药物和精神药物。大多数试验是公开的，并利用药物有效性的自我报告方法，限制了其有效性。大多数试验都指出了有益的作用。副作用和患者依从性在实践中会限制抗libidinal药物的有效性。原创性/价值由于缺乏适当控制的临床试验，用于治疗不良性行为的药理学证据非常有限。因此，需要进行新的研究，尤其是对于更大的样本量，更长的持续时间以及检查受益于药物治疗的患者的特征，