Introduction: To assess cognitive impairment, self-awareness is an important issue. The Ascertain Dementia 8 questionnaire (AD8) is a brief observation checklist for detecting mild cognitive impairment (MCI) and dementia. After analyzing the reliability and validity of a self-reported Japanese version of the AD8 (AD8-J), we compared self- and informant-reported versions of the AD8-J. Methods: A total of 93 community residents aged 75 years or older living in Wakuya, Northern Japan, agreed to participate in this study; 35 were rated as Clinical Dementia Rating (CDR) 0 (healthy), 46 as CDR 0.5 (defined herein as MCI), and 12 as CDR 1 or above (dementia, confirmed by the DSM-IV). We examined the reliability and validity using a receiver operating characteristic (ROC) curve. We analyzed the differences between self-reported and informant-reported AD8-J using a repeated measures ANOVA. Results: The self-reported AD8-J showed a satisfactory reliability (i.e., Cronbach coefficient, α = 0.71; Guttman split half method coefficient = 0.60). For CDR 0 vs. CDR 0.5 or above, the area under the ROC curve was 0.74 and the cutoff score was 1/2, with a sensitivity of 70.7% and a specificity of 65.7%. Analysis of the subscores of AD8 suggested that, from the early stage of dementia, the subjects showed a subjective decline in memory and interest in hobbies/activities, as well as problems with judgment. Conclusion: It is suggested that the self-reported AD8-J was effective in detecting MCI and dementia. We could use it for detecting MCI and dementia, including in those living alone, in the primary health checkup.
Dement Geriatr Cogn Disord Extra 2021;11:45–50

中文翻译：

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基于 Ascertain Dementia 8 问卷的自我报告认知衰退可能有效检测社区中的轻度认知障碍和痴呆症：Wakuya 项目

简介：为了评估认知障碍，自我意识是一个重要问题。Ascertain Dementia 8 问卷 (AD8) 是一个简短的观察清单，用于检测轻度认知障碍 (MCI) 和痴呆。在分析了自我报告的日本版 AD8 (AD8-J) 的可靠性和有效性之后，我们比较了 AD8-J 的自我报告版本和线人报告的版本。方法：共有 93 名居住在日本北部 Wakuya 的 75 岁或以上的社区居民同意参加这项研究；35 人被评为临床痴呆评分 (CDR) 0（健康），46 人被评为 CDR 0.5（本文定义为 MCI），12 人被评为 CDR 1 或以上（痴呆，由 DSM-IV 确认）。我们使用受试者工作特征 (ROC) 曲线检查了信度和效度。我们使用重复测量方差分析分析了自我报告和线人报告的 AD8-J 之间的差异。结果：自我报告的 AD8-J 显示出令人满意的可靠性（即 Cronbach 系数，α = 0.71；Guttman 分半法系数 = 0.60）。对于 CDR 0 vs. CDR 0.5 或以上，ROC 曲线下面积为 0.74，截止分数为 1/2，敏感性为 70.7%，特异性为 65.7%。对 AD8 子评分的分析表明，从痴呆的早期阶段开始，受试者就表现出记忆力和对爱好/活动的兴趣的主观下降，以及判断力的问题。结论：表明自我报告的AD8-J在检测MCI和痴呆方面是有效的。我们可以在初级健康检查中使用它来检测 MCI 和痴呆症，包括独居者。
Dement Geriatr Cogn Disord Extra 2021；11：45–50