Lambs born from dairy ewes are removed from their mothers within hours of ingesting colostrum; this influences their growth and development, especially when artificial milk has poor quality or insufficient volume. Alternatives have been proposed to assist lambs during this phase, including providing concentrate with additives such as choline, which is involved in various physiological processes. This study's objective was to determine the effects of vegetable biocholine (VB) supplementation on growth, biochemistry, and antioxidant responses in lambs from dairy ewes during the feed transition period. We used 40 Lacaune lambs in a randomized block design, distributed in four groups with five replications (two animals per replication). VB was added to the concentrate and was consumed between 30 days pre-weaning to 30 days post-weaning (total 60 days). The treatments were as follows: T0, without added VB, control group; T2, 2 g VB per animal/day; T4, 4 g VB per animal/day; and T6, 6 g VB per animal/day. The weight gain increased in T2, T4, and T6 lambs when compared to T0. Using orthogonal polynomials analysis suggested that the ideal supplementation dose is 2.81 g/day per animal when considering the maximum average daily gain (ADG), which corresponds to 0.189 g VB/kg of body weight (BW). After weaning, there were lower serum concentrations of creatine kinase enzyme in lambs supplemented with VB than in controls. No differences were observed concerning levels of total protein, albumin, or globulins. Alanine aminotransferase (ALT) activity of T2 and T4 lambs was greater only at weaning (30 days). Glucose was greater in T2 and T4 lambs only on day 15. In general, VB supplementation decreased serum levels of reactive oxygen species (ROS) from day 15 of supplementation; these animals had lower lipid peroxidation levels after weaning. The activities of glutathione S-transferase (GST) did not differ. These data suggest that supplementation with VB increases weight gain and improves health, primarily by reducing free radical levels during the dietary transition period.

在摄取初乳后的数小时内，将由母乳母羊产下的羔羊从其母体中取出。这会影响它们的生长和发育，尤其是当人造乳的质量较差或体积不足时。已经提出了在该阶段协助羔羊的替代方法，包括向精矿提供诸如胆碱的添加剂，这涉及各种生理过程。这项研究的目的是确定在饲料过渡期间补充蔬菜生物胆碱（VB）对奶母羊羔生长，生物化学和抗氧化反应的影响。我们在随机区组设计中使用了40只Lacaune羔羊，分为4组，每组5个重复（每个重复2只动物）。将VB添加到浓缩物中，并在断奶前30天至断奶后30天（总共60天）之间食用。处理方法如下：对照组，不加VB的T0组；对照组。T2，每只动物/天2 g VB；T4，每只动物/天4 g VB；和T6，每只动物/天6 g VB。与T0相比，T2，T4和T6羔羊的体重增加。使用正交多项式分析表明，考虑到最大平均日增重（ADG），每只动物的理想补充剂量为2.81 g /天，相当于0.189 g VB / kg体重（BW）。断奶后，补充VB的羔羊的血清肌酸激酶浓度低于对照组。在总蛋白，白蛋白或球蛋白水平上未观察到差异。仅在断奶时（30天），T2和T4羔羊的丙氨酸氨基转移酶（ALT）活性更高。仅在第15天，T2和T4羔羊的血糖更高。一般而言，VB补充剂从补充的第15天起降低了血清活性氧（ROS）的水平。这些动物断奶后脂质过氧化水平较低。谷胱甘肽S-转移酶（GST）的活性没有差异。这些数据表明，主要通过在饮食过渡期间降低自由基水平，补充VB可以增加体重并改善健康。谷胱甘肽S-转移酶（GST）的活性没有差异。这些数据表明，主要通过在饮食过渡期间降低自由基水平，补充VB可以增加体重并改善健康。谷胱甘肽S-转移酶（GST）的活性没有差异。这些数据表明，主要通过在饮食过渡期间降低自由基水平，补充VB可以增加体重并改善健康。