Acorus calamus (AC), is an herbal medicine commonly used as traditional practice in pharmacological applications. Present study initiated was evident to proof the hepatoprotective and nephroprotective activity with supporting histopathological status of kidneys and liver. Investigation done with the 5% (w/v) of AC dissolved in tap water (50 g/l) given for 15 days compared with control tap water to 5-7 week old C57Bl/6 mice both sexes. Renal function, liver function, biochemical and complete blood count was evaluated. AC significantly reduced food intake, body weight, also plasma concentration of electrolytes such as Na⁺, K⁺, Ca²⁺, were reduced as the excretion of electrolytes were increased in urine, significantly increased Fluid Intake, with Urinary urea, Urinary creatinine, Glomerular Filtration Rate, creatinine clearance, High-density lipoproteins, Mean Corpuscular Volume. The biochemical findings showed the hepatoprotective and histopathological changes showed the nephroprotective nature of AC by normal structure with no necrosis.

cor蒲（AC）是一种在药理学应用中通常用作传统做法的草药。目前启动的研究很明显地证明了其对肝和肾的保护作用以及对肾脏和肝脏组织病理学状态的支持。用5％（w / v）AC溶解在自来水（50g / l）中的AC进行了15天的研究，与对照自来水相比，性别为5-7周龄的C57Bl / 6小鼠。评估肾功能，肝功能，生化和全血细胞计数。交流电可显着减少食物摄入量，体重以及电解质的血浆浓度，例如Na ⁺，K ⁺，Ca ²⁺随着尿液中电解质的排泄增加，尿素，尿素减少，尿液，尿肌酐，肾小球滤过率，肌酐清除率，高密度脂蛋白，平均小细胞体积显着增加。生化结果表明，肝脏的保护作用和组织病理学变化表明，正常结构的AC具有肾脏保护作用，而没有坏死。