This study seeks to determine if members of a pediatric (<18 years) sample who have high levels of the urinary volatile organic compound (VOC) metabolite of acrylonitrile, N-Acetyl-S-(2-cyanoethyl)-l-cysteine (CYMA), are significantly more likely to be living in a household with indoor tobacco smoke exposure. A weighted logistic regression was used to compare pediatric participants in the highest quartile of CYMA levels (≥ 4.56 ng/mL) with those whose CYMA levels were not in the highest quartile. 411 pediatric participants were identified in the NHANES data for analysis. Those in the highest quartile of recorded CYMA values were more likely to be living with active indoor smokers (69.35 %) than those who were not in the highest quartile (32.72 %). Having one indoor smoker (adjusted-OR: 2.53, 95 % CI: 1.01–6.34) or 2+ indoor smokers (adjusted-OR: 4.25, 95 % CI: 1.84–9.81) were both associated with a pediatric participant having a CYMA value in the highest quartile.

本研究旨在确定是否儿科的成员（<18岁）样品谁有高水平泌尿挥发性有机化合物（VOC）的丙烯腈代谢物，N-乙酰基-S-（2-氰乙基） -升-半胱氨酸（CYMA）更有可能生活在暴露于室内烟草烟雾的家庭中。加权对数回归用于比较CYMA水平最高四分位数（≥4.56 ng / mL）的儿科参与者与CYMA水平不在最高四分位数的小儿受试者。在NHANES数据中确定了411名儿科参与者进行分析。记录的CYMA值最高的四分位数的人更有可能与活跃的室内吸烟者住在一起（69.35％），而不是那些不在最高四分位数的人（32.72％）。有一名室内吸烟者（调整后的OR：2.53，95％CI：1.01-6.34）或2+室内吸烟者（调整后的OR：4.25，95％CI：1.84-9.81）均与具有CYMA值的儿科受试者相关在最高的四分位数中