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Exploring the diagnostic value of photoacoustic imaging for breast cancer: the identification of regional photoacoustic signal differences of breast tumors
Biomedical Optics Express ( IF 2.9 ) Pub Date : 2021-02-16 , DOI: 10.1364/boe.417056
Rui Zhang 1 , Ling-yi Zhao 2 , Chen-yang Zhao 1 , Ming Wang 1 , Si-rui Liu 1 , Jian-chu Li 1 , Rui-na Zhao 1 , Ruo-jiao Wang 1 , Fang Yang 3 , Lei Zhu 3 , Xu-jin He 3 , Chang-hui Li 2 , Yu-xin Jiang 1 , Meng Yang 1
Affiliation  

We examined 14 benign and 26 malignant breast nodules by a handheld dual-modal PA/US imaging system and analyzed the data using the quantitative and semi-quantitative method. The PA signal spatial density and PA scores of different regions of the benign and malignant nodules were compared, and the diagnostic performances of two diagnostic methods based on PA parameters were evaluated. For both quantitative and semi-quantitative results, significant differences in the distributions of PA signals in different regions of benign and malignant breast lesions were identified. The PA parameters showed good performance in diagnosing breast cancer, indicating the potential of PAI in clinical utilization.

中文翻译:

探索光声成像对乳腺癌的诊断价值:确定乳腺肿瘤的区域光声信号差异

我们通过手持式双模态PA / US成像系统检查了14个良性和26个恶性乳腺结节,并使用定量和半定量方法分析了数据。比较了良,恶性结节不同区域的PA信号空间密度和PA评分,并评估了两种基于PA参数的诊断方法的诊断性能。对于定量和半定量结果,在良性和恶性乳腺病变的不同区域中,PA信号的分布均存在显着差异。PA参数在诊断乳腺癌中表现出良好的性能,表明PAI在临床应用中的潜力。
更新日期:2021-03-01
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