Radiotherapy of extensive malignant scalp lesions has always been a challenge for radiation oncologists considering the proximity of critical structures.

We treated a 39-year-old patient with extensive scalp squamous cell carcinoma with application of adjuvant concurrent chemoradiation and external beam radiation therapy (EBRT), followed by high-dose-rate (HDR) surface brachytherapy boost using an exclusively designed mould, and assessed the radiation dose reaching planning target volume, brain, and optic structures.

Comparison between conventional planning with sole EBRT and combined treatment planning with EBRT and brachytherapy, assured the use of the latter treatment to avoid high radiation doses from reaching critical organs at risk without compromising the required dose for planning target volume.

中文翻译：

---

光子束放疗与近距离放射治疗相结合的新方法治疗广泛的晚期头皮鳞状细胞癌

考虑到关键结构的邻近性，广泛的恶性头皮病变的放射治疗一直是放射肿瘤学家的挑战。

我们采用辅助同时放化疗和外部束放射疗法（EBRT），并采用专门设计的模具进行高剂量率（HDR）表面近距离放射治疗，治疗了39岁的广泛头皮鳞状细胞癌患者。评估达到计划目标体积，大脑和视神经结构的辐射剂量。

单独采用常规EBRT的常规计划与采用EBRT和近距离放射治疗的联合治疗计划之间的比较，确保了采用后一种治疗方法，以避免高剂量的放射线到达有风险的关键器官，而不会损害规划目标量所需的剂量。