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In vivo anti-inflammatory activity of Fabaceae species extracts screened by a new ex vivo assay using human whole blood
Phytochemical Analysis ( IF 3.0 ) Pub Date : 2021-02-16 , DOI: 10.1002/pca.3031 Welton Rosa 1 , Olívia da Silva Domingos 1 , Paula Pio de Oliveira Salem 1 , Ivo Santana Caldas 2 , Michael Murgu 3 , João Henrique Ghilardi Lago 4 , Patricia Sartorelli 5 , Danielle Ferreira Dias 1 , Daniela Aparecida Chagas-Paula 1 , Marisi Gomes Soares 1
Phytochemical Analysis ( IF 3.0 ) Pub Date : 2021-02-16 , DOI: 10.1002/pca.3031 Welton Rosa 1 , Olívia da Silva Domingos 1 , Paula Pio de Oliveira Salem 1 , Ivo Santana Caldas 2 , Michael Murgu 3 , João Henrique Ghilardi Lago 4 , Patricia Sartorelli 5 , Danielle Ferreira Dias 1 , Daniela Aparecida Chagas-Paula 1 , Marisi Gomes Soares 1
Affiliation
Plants have been considered a promising source for discovering new compounds with pharmacological activities. The Fabaceae family comprises a large variety of species that produce substances with diverse therapeutic potential, including anti-inflammatory activity. The limitations of current anti-inflammatories generate the need to research new anti-inflammatory structures with higher efficacy as well as develop methods for screening multiple samples, reliably and ethically, to assess such therapeutic properties.
中文翻译:
豆科植物提取物的体内抗炎活性通过使用人全血的新离体试验筛选
植物被认为是发现具有药理活性的新化合物的有希望的来源。豆科植物种类繁多,可产生具有多种治疗潜力的物质,包括抗炎活性。当前抗炎药的局限性导致需要研究具有更高功效的新抗炎结构,并开发可靠且合乎道德的筛选多个样本的方法,以评估此类治疗特性。
更新日期:2021-02-16
中文翻译:
豆科植物提取物的体内抗炎活性通过使用人全血的新离体试验筛选
植物被认为是发现具有药理活性的新化合物的有希望的来源。豆科植物种类繁多,可产生具有多种治疗潜力的物质,包括抗炎活性。当前抗炎药的局限性导致需要研究具有更高功效的新抗炎结构,并开发可靠且合乎道德的筛选多个样本的方法,以评估此类治疗特性。