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A comprehensive review on the health benefits and nutritional significance of fucoidan polysaccharide derived from brown seaweeds in human, animals and aquatic organisms
Aquaculture Nutrition ( IF 3.0 ) Pub Date : 2021-02-15 , DOI: 10.1111/anu.13233
Muhammad Saeed 1 , Muhammad A. Arain 2 , Sarfraz Ali Fazlani 2 , Illahi B. Marghazani 2 , Muhammad Umar 2 , Jameela Soomro 3 , Zohaib A. Bhutto 2 , Feroza Soomro 3 , Ahmed E. Noreldin 4 , Mohamed E. Abd El‐Hack 5 , Shaaban S. Elnesr 6 , Mayada R. Farag 7 , Kuldeep Dhama 8 , Sun Chao 9 , Mahmoud Alagawany 5
Affiliation  

Fucoidan is a sulphated polysaccharide isolated from brown seaweeds. It has attracted a lot of attention due to its multiple physiological and biological properties. The most dominant polysaccharides in brown seaweeds are laminarin and alginic acid. Fucoidan extracted from brown seaweed possess various biological functions including anti‐inflammatory, immunomodulatory, antitumour, antibacterial, antiviral, anticoagulant, antioxidant, neuroprotective, cardio‐protection and growth‐promoting effects. Dietary supplementation of fucoidan showed significant therapeutic influences on aquatic organisms, human, livestock and poultry. This review highlights the medicinal importance and nutritional values of fucoidan polysaccharides for fish, animals and humans, to be used as a natural agent for the treatment of various pathological disorders and to replace the synthetic antibiotics. Previously, most studies are focused on in vitro model and in mice. Further studies are warranted on in vivo model and focusing on a molecular basis to understand the mechanisms of action of fucoidan as an alternative therapeutic drug for fish, animals and humans. Another objective of this review is to give more light about the beneficial impacts of fucoidan on productive performance of animals and poultry as well as aquatic organisms.

中文翻译:

褐藻中的岩藻依聚糖多糖对人类,动物和水生生物的健康益处和营养意义的全面综述

岩藻依聚糖是从褐藻中分离出来的一种硫酸化多糖。由于其多种生理和生物学特性,它引起了很多关注。棕色海藻中最主要的多糖是laminarin和藻酸。从褐藻中提取的褐藻多糖具有多种生物学功能,包括抗炎,免疫调节,抗肿瘤,抗菌,抗病毒,抗凝,抗氧化剂,神经保护,心脏保护和促进生长的作用。膳食补充岩藻依聚糖对水生生物,人类,牲畜和家禽显示出显着的治疗作用。这篇评论强调了岩藻依聚糖多糖对鱼类,动物和人类的药用重要性和营养价值,用作治疗各种病理疾病的天然药物并替代合成抗生素。以前,大多数研究都集中在体外模型和小鼠中。需要在体内模型上进行进一步的研究,并集中在分子基础上,以了解岩藻依聚糖作为鱼类,动物和人类的替代治疗药物的作用机理。这篇综述的另一个目的是提供更多关于岩藻依聚糖对动物和家禽以及水生生物生产性能的有益影响的信息。
更新日期:2021-02-15
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