Humans, animals, and the environment face a universal crisis: antimicrobial resistance (AR). Addressing AR and its multi-disciplinary causes across many sectors including in human and veterinary medicine remains underdeveloped. One barrier to AR efforts is an inconsistent process to incorporate the plenitude of stakeholders about what AR is and how to stifle its development and spread—especially stakeholders from the animal agriculture sector, one of the largest purchasers of antimicrobial drugs. In 2019, The Wellcome Trust released Reframing Resistance: How to communicate about antimicrobial resistance effectively (Reframing Resistance), which proposed the need to establish a consistent and harmonized messaging effort that describes the AR crisis and its global implications for health and wellbeing across all stakeholders. Yet, Reframing Resistance does not specifically engage the animal agriculture community. This study investigates the gap between two principles recommended by Reframing Resistance and animal agriculture stakeholders. For this analysis, the research group conducted 31 semi-structured interviews with a diverse group of United States animal agriculture stakeholders. Participants reported attitudes, beliefs, and practices about a variety of issues, including how they defined AR and what entities the AR crisis impacts most. Exploration of Reframing Resistance’s Principle 2, “explain the fundamentals succinctly” and Principle 3, “emphasis that this is universal issue; it can affect anyone, including you” reveals disagreement in both the fundamentals of AR and consensus of “who” the AR crisis impacts. Principle 2 may do better to acknowledge that animal agriculture stakeholders espouse a complex array of perspectives that cannot be summed up in a single perspective or principle. As a primary tool to combat AR, behavior change must be accomplished first through outreach to stakeholder groups and understanding their perspectives.

人类、动物和环境面临着普遍的危机：抗菌素耐药性 (AR)。解决包括人类医学和兽医学在内的许多部门的 AR 及其多学科原因仍然不发达。AR 工作的一个障碍是，将大量利益相关者纳入 AR 是什么以及如何扼杀其发展和传播的过程不一致，尤其是来自动物农业部门的利益相关者，该部门是抗菌药物的最大购买者之一。2019 年，惠康基金会发布了Reframing Resistance：如何有效地沟通抗菌素耐药性（Reframing Resistance），它提出需要建立一致和协调的信息传递工作，以描述 AR 危机及其对所有利益相关者的健康和福祉的全球影响。然而，Reframing Resistance并没有专门让畜牧业社区参与进来。本研究调查了Reframing Resistance和畜牧业利益相关者推荐的两项原则之间的差距。为了进行这项分析，研究小组对不同的美国畜牧业利益相关者群体进行了 31 次半结构化访谈。参与者报告了对各种问题的态度、信念和做法，包括他们如何定义 AR 以及 AR 危机对哪些实体影响最大。重构阻力的探索原则二，“简明扼要地解释基本原理”和原则三，“强调这是一个普遍问题；它可以影响任何人，包括你”揭示了 AR 的基本原理和 AR 危机影响“谁”的共识的分歧。原则 2 可能会更好地承认畜牧业利益相关者支持一系列复杂的观点，这些观点无法用单一观点或原则来概括。作为对抗 AR 的主要工具，行为改变必须首先通过接触利益相关者群体并了解他们的观点来实现。