There are few efficacious pharmacological treatments for posttraumatic stress disorder (PTSD) and many patients fail to benefit from existing treatments. Vortioxetine, a recently developed antidepressant, acts as a serotonin modulator through inhibition of the serotonin transporter and actions at multiple types of serotonin receptors. Its unique pharmacodynamic profile suggests it may have efficacy for the treatment of PTSD.

中文翻译：

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沃替西汀单药治疗创伤后应激障碍的疗效：一项随机、安慰剂对照试验。

创伤后应激障碍 (PTSD) 的有效药物治疗很少，许多患者无法从现有治疗中受益。Vortioxetine 是一种最近开发的抗抑郁药，通过抑制 5-羟色胺转运体和作用于多种类型的 5-羟色胺受体，起到 5-羟色胺调节剂的作用。其独特的药效学特征表明它可能对治疗 PTSD 有效。