Extract from Ascaris suum and N‐acetyl‐L‐cysteine induces an immunosuppressant effect in model of autoimmune hepatitis,Parasite Immunology

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Extract from Ascaris suum and N‐acetyl‐L‐cysteine induces an immunosuppressant effect in model of autoimmune hepatitis
Parasite Immunology ( IF 1.4 ) Pub Date : 2021-02-15 , DOI: 10.1111/pim.12826
Roeckson Carlos Peixoto Silva _{1,

2} , Raul Penaforte Correia da Silva _{1,

2} , Fabrício Oliveira Souto _{1,

3} , Virginia Maria Barros de Lorena ₄ , André de Lima Aires _{1,

2} , Vlaudia Maria Assis Costa _{1,

2} , Mônica Camelo Pessôa de Azevedo Albuquerque _{1,

2} , Valdênia Maria Oliveira de Souza _{1,

5}

Affiliation

Extract of adult Ascaris suum (ASC) worms attenuated the liver damage in experimental autoimmune hepatitis (EAH) with induction of Th2 immune response, but fibrosis occurred. N‐acetyl‐L‐cysteine (NAC) has protective effects against liver fibrosis.

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