Significant concentrations of pharmaceuticals and personal care products (PPCPs) have been detected in aquatic environment. Fungal enzymatic processes can oxidize these persistent PPCPs; thus, these processes have attracted considerable attention from the scientific community. Here, we evaluated the efficacy of the removal of PPCPs using native fungal enzymes derived from Bjerkandera spp. TBB-03 under various conditions. Among the eight lignocellulosic substrates, ash, which showed the highest laccase production, was selected as the sole enzyme inducer. TBB-03 laccase was found to exhibit remarkable stability under varied pH and temperature conditions. Acetaminophen and bisphenol A were effectively removed by TBB-03 laccase under various conditions, except at pH 8. Although TBB-03 laccase could not efficiently remove single-state sulfamethoxazole directly, a 22% of improvement in sulfamethoxazole removal was observed in the presence of acetaminophen. Overall, our proposed approach showed that Bjerkandera adusta TBB-03 can be potentially applied for further research regarding PPCP remediation.

在水生环境中已检测到大量药物和个人护理产品（PPCP）。真菌的酶促过程可以氧化这些持久性PPCP。因此，这些过程引起了科学界的极大关注。在这里，我们评估了使用源自Bjerkandera的天然真菌酶去除PPCP的功效spp。TBB-03在各种条件下。在八种木质纤维素底物中，灰分显示出最高的漆酶产量，被选作唯一的酶诱导剂。发现TBB-03漆酶在变化的pH和温度条件下表现出显着的稳定性。除pH值为8外，TBB-03漆酶在各种条件下均可有效去除对乙酰氨基酚和双酚A。尽管TBB-03漆酶无法直接有效去除单态磺胺甲基异恶唑，但在存在HBs的情况下，磺胺甲基恶唑的去除率提高了22％。对乙酰氨基酚。总体而言，我们提出的方法表明Bjerkandera adusta TBB-03可以潜在地用于有关PPCP修复的进一步研究。