Nonthermal plasma is suitable for applications in the biomedical field because of the large amounts of active species and a low gas temperature that does not injure the human body. A plasma jet of the typical pen type is applied in most biomedical applications, but it is difficult to apply such jets to treat skin diseases that generally have wide affected areas. In this study, nonthermal multineedle dielectric barrier discharge (DBD) jet was developed for the treatment of large area lesions and used to verify its effectiveness in treating psoriasis as a representative skin disease. Stable discharge was maintained using the developed plasma jet with a multineedle electrode structure by utilizing various discharge gases. Electrical and optical analyses were performed to determine the characteristics of the plasma. The effectiveness of psoriasis treatment using this approach was confirmed by performing in vitro and in vivo experiments with the multineedle DBD jet.

非热等离子体适用于生物医学领域，因为存在大量的活性物质，并且气体温度较低，不会伤害人体。典型笔型的等离子射流用于大多数生物医学应用中，但是很难将这种射流用于治疗通常具有广泛感染区域的皮肤疾病。在这项研究中，非热多针电介质屏障放电（DBD）射流被开发用于治疗大面积病变，并用于验证其在治疗牛皮癣中作为代表性皮肤病的有效性。使用开发的具有多针电极结构的等离子流，通过使用各种放电气体，可以保持稳定的放电。进行电学和光学分析以确定等离子体的特性。