Objective

To investigate the effects of resistance exercise (RE) on body structure and function, activity, and participation in individuals with Parkinson Disease (PD) in the mild to moderate stages.

Data Sources

Medline, Embase, Web of Science, The Cochrane Library, Lilacs, and PEDro were searched from inception until June 2020 using the terms “Parkinson Disease,” “Exercise,” “Resistance Training,” “Muscle Strength,” “Cardiorespiratory Fitness,” “Postural Balance,” “Gait,” and “Quality of Life.”

Study Selection

We included studies conducted in individuals with PD involving RE compared with a control group. Two independent reviewers performed the selection process based on titles, abstracts, and full-text reading. In total, 270 individuals with PD were included from 10 selected studies.

Data extraction

Two reviewers independently extracted characteristics related to participants, intervention and control types, and results. The PEDro scale was used to assess the methodological quality, and the level of evidence was analyzed and synthesized using the Grading of Recommendation, Assessment, Development, and Evaluations approach.

Data Synthesis

The level of evidence for body structure and function was low and without effect for lower limb muscle strength; very low and with effect for upper limb muscle strength, cardiorespiratory fitness, and postural balance; and very low and without effect for flexibility after RE training. For activity, the evidence was very low and with effect for gait and very low and without effect for mobility. For participation (ie, quality of life) the evidence was very low and without effect.

Conclusions

Although the level of evidence was low to very low, RE was shown to promote improvements in body structure and function (upper limb muscle strength, cardiovascular function, postural balance) and activity (gait). In contrast, RE did not significantly improve participation (quality of life). However, based on the present findings, the practice of RE can be recommended for individuals with PD in the mild to moderate stages.

中文翻译：

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抗阻运动对帕金森病患者身体结构和功能、活动和参与的影响：系统评价

客观的

研究抗阻运动 (RE) 对轻度至中度帕金森病 (PD) 患者的身体结构和功能、活动和参与的影响。

数据源

Medline、Embase、Web of Science、Cochrane 图书馆、Lilacs 和 PEDro 从开始到 2020 年 6 月使用“帕金森病”、“锻炼”、“阻力训练”、“肌肉力量”、“心肺健康”等术语进行搜索。 “姿势平衡”、“步态”和“生活质量”。

研究选择

我们纳入了与对照组相比，在涉及 RE 的 PD 个体中进行的研究。两名独立审稿人根据标题、摘要和全文阅读进行了选择过程。总共有 270 名 PD 患者来自 10 项选定的研究。

数据提取

两名评价者独立提取与参与者、干预和控制类型以及结果相关的特征。PEDro 量表用于评估方法学质量，并使用推荐分级、评估、开发和评估方法分析和综合证据水平。

数据综合

身体结构和功能的证据水平低，对下肢肌肉力量没有影响；非常低，对上肢肌肉力量、心肺健康和姿势平衡有影响；并且非常低并且对 RE 训练后的灵活性没有影响。对于活动，证据非常低且对步态有影响，而证据非常低且对活动性没有影响。对于参与（即生活质量），证据非常低且没有效果。

结论

尽管证据水平从低到非常低，但 RE 被证明可以促进身体结构和功能（上肢肌肉力量、心血管功能、姿势平衡）和活动（步态）的改善。相比之下，RE 并没有显着提高参与度（生活质量）。然而，根据目前的研究结果，可以向轻度至中度阶段的 PD 患者推荐 RE 的实践。