Irish physician Sir Matthew John Tierney (1776–1845) was a vaccine pioneer who learnt the procedure directly from Edward Jenner in Gloucestershire. In 1802 Tierney completed an MD at Glasgow on vaccination and moved to Brighton, where he was appointed physician to the Prince of Wales (the future King George IV). This paper considers Tierney’s role in the foundation of the 1804 Sussex Vaccine Institution. Tierney was the first president of the Institution’s Medical Council. His leadership lay in his knowledge of vaccination (including transporting cowpox material) and his close relationship with the Prince of Wales. The Institution’s official name was the Royal Sussex Jennerian Society for the Extermination of the Small-pox and offered vaccination at 16 stations across the county and one in Kent. Vaccination was undertaken by local surgeons at their houses at set hours. In its first year, the Institution vaccinated 946 individuals, of whom 509 for free. Despite this, concerns were raised over uptake by poorer members of society. The Institution’s Brighton station was probably absorbed into the new 1809 dispensary. Tierney’s promotion of vaccination and instructions for new practitioners represent the embryonic beginnings of evidence-based medicine and modern medical education in Brighton.

中文翻译：

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马修·蒂尔尼爵士和 1804 年苏塞克斯疫苗机构的成立

爱尔兰医生马修·约翰·蒂尔尼爵士（1776-1845 年）是一位疫苗先驱，他直接从格洛斯特郡的爱德华·詹纳那里学习了该程序。1802 年，蒂尔尼在格拉斯哥完成了疫苗接种的医学博士学位，并搬到了布莱顿，在那里他被任命为威尔士亲王（未来的乔治四世国王）的医生。本文考虑了蒂尔尼在 1804 年苏塞克斯疫苗机构的建立中的作用。蒂尔尼是该机构医学委员会的第一任主席。他的领导力在于他的疫苗接种知识（包括运输牛痘材料）以及他与威尔士亲王的密切关系。该机构的正式名称是皇家苏塞克斯詹纳天花消灭协会，并在全县的 16 个站点和肯特的一个站点提供疫苗接种。当地外科医生在规定的时间在家中接种疫苗。第一年，该机​​构为 946 人接种了疫苗，其中 509 人是免费的。尽管如此，人们还是对社会较贫穷成员的吸收提出了担忧。该机构的布莱顿站可能并入了 1809 年的新药房。Tierney 对新从业者的疫苗接种和指导的推广代表了布莱顿循证医学和现代医学教育的萌芽。