The Yangtze River Economic Zone (YREZ) is a major corridor of national science and innovation culture, an innovation-driven region that fosters new drivers of growth and leads transformation and development, and plays an important strategic support and exemplary leading role in the overall pattern of regional development. This paper analyzes the spatiotemporal differentiation characteristics of innovation output of 110 cities of YREZ from 2008 to 2018 by using Gini coefficient, coefficient of variation (CV), geographical weighted regression, and other methods. The factors affecting innovation output are selected from the perspective of innovation ecosystem. The results show the following. (1) Innovation output showed an increasing trend, and the high-value concentration cities in downstream areas gradually became prominent, the geographical concentration degree fluctuated and declined, and the distribution of innovation output gradually became balanced. (2) The global Moran’s I index of innovation output shows a fluctuation pattern of “M” shape and an overall upward trend. The analysis of local spatial correlation indicates that spatial distribution pattern of innovation output has not changed significantly. (3) There is obvious regional heterogeneity under different impacts of factors of innovation ecosystem on innovation output. Enterprises have the greatest impact, followed by financial resources and infrastructure environment.

中文翻译：

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长江经济区创新产出的时空异质性与驱动力分析：创新生态系统的视角

长江经济区是国家科技创新文化的主要走廊，是一个以创新为驱动力的地区，它培育了新的增长动力并带动了转型与发展，并在总体格局中发挥了重要的战略支持和示范领导作用区域发展。本文运用基尼系数，变异系数（CV），地理加权回归等方法分析了扬州市经济技术开发区110个城市2008年至2018年创新产出的时空差异特征。从创新生态系统的角度选择影响创新产出的因素。结果显示如下。（1）创新产出呈增长趋势，下游高价值集中城市逐渐凸显；地域集中度上下波动，创新产出分布逐渐趋于平衡。（2）全球Moran's创新输出指数I呈“ M”形波动格局，总体呈上升趋势。局部空间相关性分析表明，创新产出的空间分布格局没有明显变化。（3）在创新生态系统因素对创新产出的不同影响下，存在明显的区域异质性。企业影响最大，其次是财务资源和基础架构环境。