A series of samarium (Sm) doped hydroxyapatites containing strontium (Sr) with controllable and adjustable luminescence were designed and prepared via chemical hydrolysis co-precipitation method. The effects of doping concentration of Sm on the structure, composition, photoluminescence (PL), energy transfer, substitute site, fluoresce lifetime and luminescence color of samples were investigated. It is shown that the introduction of Sr ions induces the structure and composition change for Sm doped samples. The typical transitions of Sm³⁺ at 564, 601, 648 and 707 nm due to ⁴G_5/2→⁶H_J/2 (J = 5, 7, 9 and 11) transition under the excitation of 404 nm were detected. The PL intensity is affected by the Sr/Ca ratio and Sm concentration, and the optimal concentration of Sm is 0.8 mol% when Sr/Ca ratio equals 7/3. The non-radiative transitions and energy transfer of Sm ions are the main reason for the quenching, and the interactions among ions are ascribed to dipole–dipole type by theoretical calculation. Besides, the ratio of PL intensity between 601 and 648 nm (r_O/R = I_{601 nm}/I_{648 nm}) indicates the symmetry and substitution process of Sm ions to Ca/Sr ions. The fluorescence lifetime (τ) decreases with the concentration of Sm increasing, which is the result of the decrease of distance and the enhanced interaction between Sm ions. The CIE chromaticity coordinates and luminescence color of samples are in the orange-red region and have close relation with the concentration of Sm. Furthermore, the cytotoxicity evaluation and confocal laser scanning microscopy (CLSM) observation of samples via cells indicate the good biocompatibility and safe use of this kind of bio-based luminescent materials for their potential efficient fluorescence labeling and detection.

采用化学水解共沉淀法设计制备了一系列发光可控、可调的钐(Sm)掺杂羟基磷灰石。研究了Sm掺杂浓度对样品结构、组成、光致发光(PL)、能量转移、取代位点、荧光寿命和发光颜色的影响。结果表明，Sr 离子的引入导致 Sm 掺杂样品的结构和组成发生变化。由于⁴ G 5/2 → ⁶ H _{J / 2} ( J ^_ = 5, 7, 9 和 11) 检测到 404 nm 激发下的跃迁。PL强度受Sr/Ca比和Sm浓度的影响，当Sr/Ca比为7/3时，Sm的最佳浓度为0.8 mol%。Sm离子的非辐射跃迁和能量转移是猝灭的主要原因，通过理论计算，离子间的相互作用属于偶极-偶极型。此外，601和648 nm之间的PL强度比（r _{O / R}  =  I _{601 nm} / I _{648 nm}）表明Sm离子与Ca / Sr离子的对称性和取代过程。荧光寿命 ( τ) 随着 Sm 浓度的增加而减小，这是距离减小和 Sm 离子间相互作用增强的结果。样品的CIE色品坐标和发光颜色在橙红色区域，与Sm的浓度有密切关系。此外，通过细胞对样品的细胞毒性评估和共聚焦激光扫描显微镜（CLSM）观察表明，这种生物基发光材料具有良好的生物相容性和安全性，可用于潜在的高效荧光标记和检测。