Cold chain, which affects human health and quality of life, is applied for temperature-sensitive and perishable products. Any problems occurring in the cold chain can cause deterioration in products, causing poisoning, death, or various diseases. There are many stages in the cold chain itself and the risk significance level of each stage is different. Therefore, the risks that occur depending on the weight of the stages in the cold chain should be defined and minimized and action plans are needed to be formed. Every action in the action plan cannot be implemented simultaneously since each action requires a different amount of budget and time resources of the companies are finite. Hence, the risks occurring in the cold chain should be minimized with the maximum use of limited company resources. In this study, an integrated mathematical model with analytical hierarchy method and failure mode and effect analysis is proposed that will maximize the weighted risk reduction amount by considering the budget and time constraints of the companies at the same time. The proposed approach has been applied in the 3PL service provider and the results are discussed. According to the results of the study where maximum benefit is aimed with the actions taken against the dangers, the maximum objective function value was obtained at the second and third levels of the workforce and budget values by evaluating the different situations with scenario analyses. In this solution, it is foreseen that by taking 5 actions, improvement will be made in 14 hazards.

影响人类健康和生活质量的冷链适用于对温度敏感且易腐的产品。冷链中发生的任何问题都可能导致产品变质，引起中毒，死亡或各种疾病。冷链本身有很多阶段，每个阶段的风险显着性水平是不同的。因此，应根据冷链中各阶段的重量来确定发生的风险，并将其最小化，并需要制定行动计划。行动计划中的每个行动不能同时执行，因为每个行动需要不同数量的预算，并且公司的时间资源是有限的。因此，应通过最大限度地利用有限的公司资源来最大程度地减少冷链中发生的风险。在这项研究中，提出了一种具有层次分析法和故障模式及效果分析的集成数学模型，该模型将通过同时考虑公司的预算和时间约束来最大化加权风险减少量。所提出的方法已在3PL服务提供商中应用，并讨论了结果。根据研究结果（最大收益旨在针对危险采取的措施），通过情景分析评估不同情况，从而在劳动力的第二和第三级获得了最大目标功能值和预算值。在该解决方案中，可以预见，通过采取5项措施，将改善14种危险。