Background: Centipeda minima (the family Asteraceae) is an annual herbaceous plant native to the tropical regions, especially in eastern tropical Asia. C. minima is well-known in the list of medicinal plants with capacities in treatment of whooping cough, nasal allergy, malaria, and asthma. More than sixty reports on phytochemical and pharmacological aspects of this plant are now available, but a supportive review is insufficient.

Objective: The current review aims to make a compilation of almost all of the isolated compounds from the title plant, together with their pharmacological activities.

Methodology: Centipeda minima is a meaningful keyword to search for previous references, while the reliable databases, such as Sci-Finder, Google Scholar, Pub Med, Science Direct, the Web of Science, Scopus, Bentham science, Taylor Francis, Springer, IOP Science were utilized at most.

Conclusion: More than one hundred secondary metabolites, classifying as terpenoids, flavonoids, mono-phenols, fatty acids, amides, and other types, were isolated from this plant. Among them, sesquiterpene lactones are dominant in either C. minima species or numerous plants of genus Centipeda. These phytochemical groups also possessed various biological results like anti-cancer, anti-bacteria, anti-allergy, anti-virus, anti-inflammation, and hepatoprotective activities. With many kinds of bioactive results such as anti-cancer and anti-inflammation, the use of C. minima plant extracts and isolated compounds for drug development seems to be a futuristic strategy.

背景：小enti（菊科）是一种一年生草本植物，原产于热带地区，特别是在亚洲东部热带地区。极小隐孢子虫在药用植物中广为人知，具有治疗百日咳，鼻过敏，疟疾和哮喘的能力。现在已有关于该植物的植物化学和药理学方面的六十多份报告，但缺乏支持性的审查。

目的：本综述旨在汇编标题植物中几乎所有分离出的化合物及其药理活性。

方法论：Centipeda minima是搜索先前参考文献的有意义的关键字，而可靠的数据库，例如Sci-Finder，Google Scholar，Pub Med，Science Direct，Web of Science，Scopus，Bentham科学，Taylor Francis，Springer，IOP科学最多被利用。

结论：从该植物中分离出了一百多种次生代谢产物，分为萜类，类黄酮，单酚，脂肪酸，酰胺和其他类型。其中，倍半萜内酯在最小梭菌物种或。属植物中占主导地位。这些植物化学基团还具有多种生物学结果，例如抗癌，抗细菌，抗过敏，抗病毒，抗炎和保肝活性。由于具有多种生物活性结果，例如抗癌和抗发炎，使用微小隐孢子虫植物提取物和分离的化合物进行药物开发似乎是一种未来的策略。