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Small cell lung cancer enters the era of precision medicine
Cancer Cell ( IF 48.8 ) Pub Date : 2021-02-11 , DOI: 10.1016/j.ccell.2021.02.002 Kristopher K Frese 1 , Kathryn L Simpson 1 , Caroline Dive 1
中文翻译:
小细胞肺癌进入精准医疗时代
更新日期:2021-03-08
Cancer Cell ( IF 48.8 ) Pub Date : 2021-02-11 , DOI: 10.1016/j.ccell.2021.02.002 Kristopher K Frese 1 , Kathryn L Simpson 1 , Caroline Dive 1
Affiliation
In this issue of Cancer Cell, Gay et al. describe a molecular classification of small cell lung cancers and extend prior studies that highlight the potential for personalized treatments. Notably, they identify a new “inflamed” subtype that may emerge following acquired chemoresistance but which may become more susceptible to immunotherapy.
中文翻译:
小细胞肺癌进入精准医疗时代
在本期《癌细胞》中,盖伊等人。描述了小细胞肺癌的分子分类,并扩展了先前的研究,强调了个性化治疗的潜力。值得注意的是,他们发现了一种新的“炎症”亚型,这种亚型可能在获得性化疗耐药后出现,但可能变得更容易受到免疫治疗的影响。