Flow biocatalysis 101: design, development and applications,Reaction Chemistry & Engineering

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Flow biocatalysis 101: design, development and applications
Reaction Chemistry & Engineering ( IF 3.4 ) Pub Date : 2021-2-3 , DOI: 10.1039/d0re00483a
Ana I. Benítez-Mateos _{1,

2,

3,

4} , Martina L. Contente _{1,

2,

3,

4} , David Roura Padrosa _{1,

2,

3,

4} , Francesca Paradisi _{1,

2,

3,

4}

Affiliation

The integration of enzyme-catalyzed reactions in flow systems has been boosted during the last few years. Nowadays, biocatalysis is officially recognized as a tool to increase reaction specificity and sustainability, however applications are sometimes characterized by low productivity. A logical step to improve the performance of biocatalytic reactions is represented by the combination of enzymes and flow facilities. This tutorial review aims at introducing the key concepts of flow biocatalysis, guiding the reader through its advantages and highlighting the current trends in the field to encourage innovative applications of enzymes in flow reactors. Experimental cases are also presented and discussed as a troubleshooting guide for development of flow biocatalytic processes.

中文翻译：

流动生物催化101：设计，开发和应用

在过去的几年中，酶催化反应在流动系统中的整合得到了加强。如今，生物催化已被公认为提高反应特异性和可持续性的工具，但有时应用的特点是生产率低。酶和流动设施的结合代表了提高生物催化反应性能的合理步骤。本教程概述旨在介绍流动生物催化的关键概念，引导读者了解其优势，并重点介绍该领域的当前趋势，以鼓励酶在流动反应器中的创新应用。还介绍和讨论了实验案例，作为开发流式生物催化过程的故障排除指南。

更新日期：2021-02-10

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